Metastatic squamous cell carcinoma arising in the setting of folliculitis decalvans

Esaa, Fatema; Shah, Pranav R.; Dolohanty, Lindsey B

doi:10.5070/d3254043590

Cited by 3 publications

(1 citation statement)

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“…Usually, after treatment, 87% of folliculitis decalvans patients achieve remission or disease control. So far, only two cases of SCC arising within folliculitis decalvans have been reported, and the tumours measured 8 mm and 2.5 cm, respectively 13 14. To our knowledge, a giant SCC arising within folliculitis decalvans on the scalp of a young AA has not been reported before.…”

Section: Discussionmentioning

confidence: 82%

Giant cutaneous squamous cell carcinoma of the scalp arising in the setting of folliculitis decalvans

et al. 2022

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Squamous cell carcinoma (SCC) is uncommon in African Americans (AAs), with an incidence of approximately 0.003%. However, it is the most common skin cancer in that patient population. In AAs, SCC typically arises in sun-protected areas and mainly affects patients older than 50 years. We report a case of giant SCC in an AA man in his 40s with long-standing folliculitis decalvans on the scalp. Three previous skin biopsies were inconclusive. A wide excision was performed and the defect was reconstructed with an anterolateral thigh free flap. Histological analysis of the resected specimen revealed a well-moderately differentiated keratinising SCC with clear cell changes, severe mixed inflammation, folliculitis and dermal scar. He was discharged 2 weeks later and has been followed up closely. Four months later, the patient presents with metastatic SCC to an occipital lymph node.

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Section: Discussionmentioning

confidence: 82%