Metastatic spine tumors

McGovern, Scott C.; Fong, Winston; Wang, Jeffrey C.

doi:10.1016/b978-0-323-06952-6.00073-7

Cited by 1 publication

(2 citation statements)

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“…The majority of symptomatic spinal metastasis are caused by breast, prostate or lung cancer [1]. The most common source of spinal metastasis in women is breast cancer, which accounts for approximately 21% of all cases of spinal metastasis [3]. Simultaneously, up to 75% of patients with advanced Breast cancer may have skeletal metastasis [4].…”

Section: Introductionmentioning

confidence: 99%

“…Pain is usually the initial presentation, which is persistent and does not respond to treatment. Pain may be accompanied by neurological symptoms, such as sensory or motor neurological deficit [3,6]. Nevertheless, studies have shown that the diagnosis of spinal cord compression frequently occurs late in the progress of spine metastasis since the initial presentations including pain may not be well recognized [7].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Review of The Currently Available Evidence for The Management of Metastatic Spinal Cord Compression Secondary to Breast Carcinoma

Aljawadi¹

2019

JPFMTS

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Background: Spine is a common site of metastasis of many primary tumors (such as, breast, prostate and lung cancer) with metastatic spinal cord compression being one of the most common sequels of this. Many management options that can be used to alleviate symptoms of spinal cord compression and/or achieve stability of the spinal cord. However, there is no consensus in the literature regarding the best treatment strategies. The purpose of this essay is to discuss the available evidence for management of metastatic spinal cord compression, including initial protection of spine stability, corticosteroids treatment, surgery and radiotherapy. Methods and Results:A comprehensive literature search conducted to retrieve the most relevant articles that were published between 1994 and 2019. The search involved multiple search engines including PubMed, ScienceDirect, Google Scholar, Web of Science, and Cochrane library. There is some evidence supports the administration of corticosteroids to alleviate the symptoms of cord compression, however side effects had been reported as an important issue. Surgery was considered the first management options for metastatic spinal cord compression in the carefully selected patients and could result in better outcomes than the other management options. Radiotherapy was associated with positive results. However, the best results were recorded when applying radiotherapy as adjunct after surgery. Conclusion:Many factors should be considered when dealing with metastatic spinal cord compression, including symptoms, spinal stability, comorbidities, and patients' preference. There was an evidence to suggest that surgery, in a carefully selected patient, may provide a better outcome compared to conservative measures.

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Section: Introductionmentioning

confidence: 99%