Metastatic seminoma presenting as flank pain

Smyth, Laura Dimmit; Davis, Niall F.; Forde, James; O’Kelly, Olive; Gupta, Rrajnish K.; Flood, Hugh D.

doi:10.5489/cuaj.1208

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“…1 Testicular cancers can present with elevated levels of human chorionic gonadotropin (hCG) and lactate dehydrogenase (LDH), however in the presence of a raised alpha-fetoprotein (AFP), this would exclude a diagnosis of pure seminoma. 2 In this report, we present a rare case of TC which had metastasized to the adrenal gland.…”

Section: Introductionmentioning

confidence: 96%

A rare case of testicular mixed germ cell tumour with adrenal metastasis

Theivendrampillai

Lockyer

Wheater

et al. 2021

Journal of Clinical Urology

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Testicular cancer commonly affects younger men, with testicular germ cell tumours comprising the vast majority of cases. They are classified into either seminomatous or non-seminomatous germ cell tumours, with mixed germ cell tumours treated as non-seminomas. In the following case report, we describe the clinical course and management of a 38-year-old male patient who presented with a right unilateral testicular mixed germ cell tumour, predominantly seminoma that had metastasized to the adrenal gland. This pattern of spread is indeed a rare occurrence. It also highlights the significance of the current diagnostic and management protocol and the benefits of using positron emission tomography as a diagnostic tool. Level of evidence: 4

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Section: Introductionmentioning

confidence: 96%