Metastatic renal cell carcinoma to ampulla of Vater: An unusual lesion amenable to surgical resection

Leslie, Kenneth A.; Tsao, Jane I.; Rossi, Ricardo L.; Braasch, John W.

doi:10.1016/s0039-6060(96)80122-x

Cited by 26 publications

(13 citation statements)

References 11 publications

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“…In terms of the surgical treatment of duodenal carcinoma, the most conventional and effective surgical method is pancreatoduodenectomy. Surgical resection of solitary metastatic renal cell carcinoma has resulted in 5-year survival rates from 35% to 50%, and a 5-year disease-free survival rate of 5% to 23% [11]. However, because of the complications and surgical massive trauma associated with this procedure and the poor condition of the patient, a less aggressive and palliative treatment was selected without treating the pancreatic tail, in order to minimize the complications and improve the quality of life.…”

Section: Resultsmentioning

confidence: 99%

A case of wedge resection of duodenum for massive gastrointestinal bleeding due to duodenal metastasis by renal cell carcinoma

Zhao

Han

et al. 2012

World J Surg Onc

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BackgroundGastrointestinal bleeding due to duodenal metastasis from renal cell carcinoma is extremely rare. Several previous reports have shown that embolic therapy or pancreatoduodenectomy (radical surgical resection) could be effective in controlling this type of clinical complication. Management is entirely dependent on the general condition and concurrent metastases at other sites. Optimizing the therapeutic strategies thus deserves further discussion and exploration.MethodsIn this report, we describe a patient with severe co-morbidities who underwent successful palliative wedge resection of duodenum and direct duodenal wall defect repair without reconstruction of duodeno-jejunostomy for acute upper digestive tract hemorrhage caused by duodenal metastasis from renal clear cell carcinoma.ResultsThe patient recovered uneventfully and did not experience rebleeding and frequent vomiting after surgery. Since then (1.5 years) he has had no evidence of rebleeding.ConclusionsGastrointestinal bleeding due to duodenal metastasis of RCC may benefit from emergent resection even in the presence of severe co-morbidities, and for palliative treatment.

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Section: Resultsmentioning

confidence: 99%

A case of wedge resection of duodenum for massive gastrointestinal bleeding due to duodenal metastasis by renal cell carcinoma

Zhao

Han

et al. 2012

World J Surg Onc

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“…Frequent sites of metastases are lung parenchyma (in 50%–60% of patients), bone (in 50%–60%), liver (in 30%–40%), and brain (in 50%). Unusual sites of metastases are characteristic of renal cancer and include the thyroid, pancreas, ampulla of Vater, skeletal muscle, and skin 4,7,8. The overall 10‐year survival rate for patients with renal cell carcinoma after nephrectomy ranges from 18% to 27% 3,9.…”

Section: Discussionmentioning

confidence: 99%

“…In only 1 patient was a nephrectomy and pancreatoduodenectomy performed simultaneously. Given the current low operative mortality associated with pancreatoduodenectomy (1%–5%) when performed by experienced surgeons who perform this procedure frequently,8 we believe that an aggressive resective approach for metastatic renal cell carcinoma to pancreas is a therapeutic method that should be considered when a potentially disease‐free state can be achieved.…”

Section: Discussionmentioning

confidence: 99%

Metastatic renal cell carcinoma to head of the pancreas successfully treated by left nephrectomy and pancreatoduodenectomy

Kanemura¹,

Fujimoto

Fujimoto³

et al. 1997

J Hep Bil Pancr Surg

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Abstract:We describe a patient with renal cell carcinoma with synchronous metastasis to the head of the pancreas who underwent left nephrectomy and pancreatoduodenectomy. The 57-year-old man was referred to us because of jaundice. Computed tomography of the abdomen showed irregular masses in the left kidney and head of the pancreas. Endoscopic retrograde cholangiopancreatography revealed a filling defect at the head of the pancreas. Renal angi0graphy demonstrated the hypervascular nature of the lesion. No other tumor lesions were discovered. The patient underwent left nephrectomy and pancreatoduodenectomy. Postoperative histopathologic examination revealed clear cell-type renal cell carcinoma in both the renal and pancreatic lesions. At follow-up 3 years later, the patient was alive without evidence of recurrent disease. We present a rare case and assess the role of aggressive surgical management for this unusual problem.

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“…The records of these five patients were reviewed. Survival rates were determined in our patients and from a review of the relevant literature, including 22 patients with well documented surgically treated pancreatic metastases from RCC . The Kaplan‐Meier method was used to estimate 3‐ and 5‐year survival rates.…”

Section: Methodsmentioning

confidence: 99%

Results of duodenopancreatectomy for solitary pancreatic metastasis from renal cell carcinoma

Tuech

Pessaux

Chautard

et al. 1999

Journal of Hepato-Biliary-Pancreatic Surgery

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The pancreas is an uncommon site of metastasis from renal cell carcinoma. We present five patients with solitary pancreatic metastasis from renal cell carcinoma located in the head of the pancreas, treated by duodenopancreatectomy. There were no perioperative deaths. Mean survival was 48 months; three patients were alive at the end of the study (at 27, 46, and 88 months, respectively) and two patients died, at 13 and 70 months. The 3- and 5-year survival rates of our patients together with 22 previously reported patients were 86% and 68%, respectively. We advocate aggressive surgical treatment when the metastatic disease is limited to the pancreas.

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Metastatic renal cell carcinoma to ampulla of Vater: An unusual lesion amenable to surgical resection

Cited by 26 publications

References 11 publications

A case of wedge resection of duodenum for massive gastrointestinal bleeding due to duodenal metastasis by renal cell carcinoma

A case of wedge resection of duodenum for massive gastrointestinal bleeding due to duodenal metastasis by renal cell carcinoma

Metastatic renal cell carcinoma to head of the pancreas successfully treated by left nephrectomy and pancreatoduodenectomy

Results of duodenopancreatectomy for solitary pancreatic metastasis from renal cell carcinoma

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