Metastatic renal cell carcinoma presenting as a chalazion

Tailor, Ramesh; Inkster, Clare; Hanson, I.; Shackley, David; Smyth, K

doi:10.1038/sj.eye.6702645

Cited by 8 publications

(5 citation statements)

References 5 publications

(4 reference statements)

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“…On the other hand, individual cases of ccRCC metastases in the eyelid have been recorded in patients with an already known primary tumor, usually after nephrectomy, as a sign of disease recurrence, as well as in patients who already have accompanying metastases in other locations [1,6,11,12]. Two cases were recorded in which chalazion was primarily diagnosed, similar to our patient, which emphasizes the importance of a good ophthalmological examination [1,5]. ccRCC is the most common type of renal carcinoma in adults, accounting for approximately 80% of cases [13].…”

Section: Discussionsupporting

confidence: 81%

“…Metastatic ccRCC of the eyelid usually presents as a painless, rapidly growing mass that may appear as a capillary hemangioma due to marked vascularization [ 4 ]. Eyelid metastases of ccRCC can also present as a typical fast-growing chalazion unresponsive to topical therapy and recurring after routine incision and curettage [ 5 ]. Patients with systemic malignant tumors usually have multiple metastatic sites, ocular and non-ocular [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

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Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report

Zrinšćak,

Kasumović,

Krolo

et al. 2024

Case Rep Oncol

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Introduction: This study is a case of solitary clear cell renal cell carcinoma (ccRCC) eyelid metastasis in a 66-year-old man as the first sign of a primary tumor. ccRCC usually spreads to the lungs, mediastinum, bones, liver, and brain, while ocular metastases are rare. Case Presentation: Solitary metastasis presented as a solid mass in the central third of the upper eyelid, which has been growing for 3 weeks. Treatment included tumor removal and blepharoplasty. Histopathological examination showed metastasis of clear cell renal carcinoma. A thorough examination revealed a primary tumor on the lower pole of the right kidney. A right nephrectomy was performed, and histopathology showed ccRCC. Postoperative examinations showed no signs of local or systemic disease. Sunitinib malate was administered to the patient. Conclusion: The eyelid metastasis in this case was still solitary and had been discovered before the existence of the primary tumor was known. Ocular metastasis of renal carcinoma is a rare initial manifestation of the disease and therefore requires a multidisciplinary approach in the treatment of these patients.

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Section: Discussionsupporting

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report

Zrinšćak,

Kasumović,

Krolo

et al. 2024

Case Rep Oncol

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show abstract

“…Occurrences of metastases from RCC to the eyelid are extremely rare, with only six cases reported during the past 10 years. [3][4][5][6] In three of them the metastasis was the first manifestation of a previously unknown RCC; however, in only one of them it was the only metastatic site, as occurred in our case. The role of surgery in the treatment of metastatic RCC is still controversial.…”

Section: Discussionsupporting

confidence: 49%

Metastatic renal cell carcinoma to the eyelid: an unusual presentation

Ramez

Hamed

Saad

2019

Journal of Clinical Urology

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Renal cell carcinoma has an unpredictable course with a propensity for metastatic spread. Here we present the case of a female patient with an unusual presentation of metastatic renal cell carcinoma to the eyelid which is extremely rare. Treatment of metastatic renal cell carcinoma is still controversial; however, several authors consider metastasectomy to be a valid option. Unfortunately, little information is available on the utility of systemic treatment after the complete resection of metastatic lesions. Level of evidence: Not applicable for this multicentre audit.

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“…Кожные метастазы ПКР описывают в 3-4,6% случаев [9]. По литературным данным, за последнее десятилетие представлено только 7 случаев метастазов ПКР в кожу века [10][11][12][13][14][15][16].…”

Section: обсуждение клинического случая и обзор литературыunclassified

A rare metastasis to the tongue and skin of the lower eyelid. A clinical case report and review of the literature

et al. 2022

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Метастатические опухоли полости рта встречаются редко. Почечно-клеточный рак (ПКР) метастазирует в органы головы и шеи в 12–16% случаев. Метастазы ПКР в язык редкое наблюдение. В мировой литературе описано 63 случая метастазирования рака почки в язык. Мы приводим клиническое наблюдение метастазирования ПКР в кожу нижнего века (как начальное проявления заболевания) и в язык (через 11 мес после постановки диагноза рак почки) у одного пациента с распространенными метастазами, включая метастазы в легкие, надпочечник, головной мозг. В статье приводим обзор литературы по данной теме.

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Metastatic renal cell carcinoma presenting as a chalazion

Cited by 8 publications

References 5 publications

Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report

Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report

Metastatic renal cell carcinoma to the eyelid: an unusual presentation

A rare metastasis to the tongue and skin of the lower eyelid. A clinical case report and review of the literature

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