Metastatic Renal Cell Carcinoma Presenting as Shoulder Monoarthritis: Diagnosis Based on Synovial Fluid Cytology and Immunocytochemistry

Galed-Placed, Ignacio; Alvarez-Rodriguez, Roberto; Pombo-Otero, Jorge; Vázquez-Bartolomé, Patricia; Hermida-Romero, Teresa; Pombo-Felipe, Francesco

doi:10.1159/000325243

Cited by 6 publications

(3 citation statements)

References 13 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…5 Other important morphologic mimics, which overlap cytologic features of brown tumours include GCT, ABC, chondroblastoma and cherubism. 1,2,[6][7][8][9] It is difficult to differentiate those entities based on cytologic features alone and appropriate clinical information such as clinical presentation, site of the lesion, laboratory tests, positive family history and imaging helps to render correct diagnosis. [10][11][12] In the present case, the smears were moderately cellular with a dual population of cells, comprising to the sheets and clusters of mononuclear cells (Figure 2A,C).…”

Section: Discussionmentioning

confidence: 99%

Cytology of a parietal swelling in a 52‐year‐old man

Bakuła‐Zalewska,

Domanski

2023

Cytopathology

View full text Add to dashboard Cite

The patient is a previously healthy 52-year-old male presented with a scalp mass, which has been enlarging over the past 6 weeks. He was admitted by a general practitioner (GP) to the fine needle aspiration (FNA) clinic. The clinical examination revealed a firm, non-tender swelling over the right occipital region with normal overlying skin (Figure 1A).FNA was performed by the cytopathologist under palpation guidance.The aspiration smear was immediately stained with Diff-Quik for an on-site examination (ROSE). After microscopic examination of the first FNA pass, two additional passes of FNA and three passes of core needle biopsy (CNB) were performed, and one aspirate was saved in the CytoLyt for cell block preparation. The core biopsies were stained with haematoxylin and eosin for histopathologic examination.After receiving the pathological report, the patient was admitted to the endocrinologic clinic. During admission, the patient presented with high blood pressure 250/100 and renal insufficiency. Blood tests revealed hypercalcemia (ionized calcium: 2.8 mmol/L) and elevated parathyroid hormone. A computed tomography scan (CT) of the brain revealed a soft tissue attenuation mass lesion measuring 48 × 42 × 27 mm with the destruction of the corresponding area of the parietal bone, extracranial soft tissue extension and intracranial extension along with the parietal lobe (Figure 1B). A subsequent CT of the neck, without and with contrast, revealed the right thyroid lobe 27-mm nodular lesion showing lower attenuering compared with the surrounding thyroid tissue. An additional 11-mm small nodule with similar attenuering was disclosed behind the lower pole of the left thyroid lobe.

show abstract

Section: Discussionmentioning

confidence: 99%

Cytology of a parietal swelling in a 52‐year‐old man

Bakuła‐Zalewska,

Domanski

2023

Cytopathology

View full text Add to dashboard Cite

show abstract

“…Bone pain and spinal cord compression are significant causes of morbidity in these patients. Metastatic RCC to the shoulder can also be a presenting feature [4], illustrating that recognition of MSS is important, especially in the context of a characteristic associated vascular or pulsatile RCC metastatic mass.…”

Section: Discussionmentioning

confidence: 99%

Malignant Shoulder Syndrome: An Under-Appreciated Feature of Renal Cell Carcinoma

McKay

2013

J Med Cases

View full text Add to dashboard Cite

show abstract

“…The latter is a syndrome presenting with coetaneous nodules and severe destructive arthritis .It may be associated with an internal malignancy. Tan et al reported two cases of MR associated with urologic malignancies (Placed et al, 2010;Tan et al2011). …”

Section: Musculoskeletal Manifestationsmentioning

confidence: 99%

Clinical Spectrum of Patients with Renal Cell Carcinoma

Gharabaghi¹

2012

Emerging Research and Treatments in Renal Cell Carcinoma

View full text Add to dashboard Cite

Metastatic Renal Cell Carcinoma Presenting as Shoulder Monoarthritis: Diagnosis Based on Synovial Fluid Cytology and Immunocytochemistry

Cited by 6 publications

References 13 publications

Cytology of a parietal swelling in a 52‐year‐old man

Cytology of a parietal swelling in a 52‐year‐old man

Malignant Shoulder Syndrome: An Under-Appreciated Feature of Renal Cell Carcinoma

Clinical Spectrum of Patients with Renal Cell Carcinoma

Contact Info

Product

Resources

About