Metastatic Oral Squamous Cell Carcinoma in a Montagu's Harrier (<i>Circus Pigargus</i>)

Ramis, Antonio; Gibert, X.; Majó, Natàlia; Grifols, Jordi

doi:10.1177/104063879901100218

Cited by 20 publications

(12 citation statements)

References 7 publications

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“…Although avian SCCs rarely metastasize, the potential to metastasize to distant organs, such as lungs, bone, spleen, and liver, which can be evaluated by radiographic technique, has been reported. 3,11,12 Therefore, radiography is an essential tool for evaluating the patient with cancer. 14 There was no sign of metastasis in the present case at either occurrence.…”

Section: Discussionmentioning

confidence: 99%

Management of a Cutaneous Squamous Cell Carcinoma in an American Flamingo (Phoenicopterus ruber)

Abu¹,

Wünschmann²,

Redig³

et al. 2009

Journal of Avian Medicine and Surgery

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A 32-year-old female American flamingo (Phoenicopterus ruber) was presented with a squamous cell carcinoma of the middle digit of the right foot. No clinical, hematologic, or radiologic evidence of metastasis was present. Salvage amputation of the digit resulted in complete cure, whereas previous electrosurgery and radiation therapy were unsuccessful. Three years later, another squamous cell carcinoma was diagnosed in the middle digit of the left foot. The digit was also amputated. Seven months after the second amputation, the bird did not have any recurrence or signs of metastasis.

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Section: Discussionmentioning

confidence: 99%

Management of a Cutaneous Squamous Cell Carcinoma in an American Flamingo (Phoenicopterus ruber)

Abu¹,

Wünschmann²,

Redig³

et al. 2009

Journal of Avian Medicine and Surgery

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“…Immunohistochemistry has proved a valuable tool for the accurate diagnosis of a number of tumors in mammals and birds (Kusewitt et al 1997, Ramis et al 1999. However, immunohistochemical characterization of neoplastic cells in reptiles has been reported in only a few cases.…”

Section: Discussionmentioning

confidence: 99%

“…However, our 2 sea turtles were juveniles. Since our findings could be related to a highly mutagenic environment, further studies determining the presence of environmental contaminants, pesticides, and heavy metals in the tissues of these turtles will be carried out.Immunohistochemistry has proved a valuable tool for the accurate diagnosis of a number of tumors in mammals and birds (Kusewitt et al 1997, Ramis et al 1999. However, immunohistochemical characterization of neoplastic cells in reptiles has been reported in only a few cases.…”

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confidence: 99%

Metastatic squamous cell carcinoma in two loggerhead sea turtles Caretta caretta

Orós

Tucker²,

Fernández³

et al. 2004

Dis. Aquat. Org.

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We received 2 stranded loggerhead sea turtles (Caretta caretta) with squamous cell carcinomas to necropsy. The dead turtles had been collected in Gran Canaria and Fuerteventura in April 1994 and May 1997, respectively to determine the cause of death. One turtle had 3 ulcerated lesions in the dorsal part of the neck and several irregular masses in the lungs and kidneys. Histologic examination of lesions in the skin, lungs, kidneys, and ventricular myocardium revealed neoplastic proliferation of abnormal keratinocytes. Ultrastructural examination identified the tumoral cells as epithelial cells. The second turtle had 4 lesions in the skin of the head and flippers, and several irregular masses in the lungs, liver, and kidneys. Histological examination revealed a squamous cell carcinoma with metastases to muscle tissue, liver, lungs, and kidneys. Attempts to characterize the tumoral cells by immunohistochemistry using several monoclonal and polyclonal antisera against high and low molecular weight cytokeratins from mammals, as well as vimentin and desmin, failed. Differences between reptilian keratins (mainly β-keratins) and mammalian keratins (mainly α-keratins) could explain this absence of immunoreactivity. This is the first description of squamous cell carcinoma in sea turtles. KEY WORDS: Squamous cell carcinoma · Loggerhead turtle · Caretta caretta · Sea turtle · Reptile · Immunohistochemistry Resale or republication not permitted without written consent of the publisherDis Aquat Org 58: [245][246][247][248][249][250] 2004 of 20 to 30 turtles per year. We report here the histopathological features of 2 cases of metastasizing squamous cell carcinoma in the loggerhead sea turtle Caretta caretta. MATERIALS AND METHODSWithin a 3 yr period (i.e. in April 1994 and May 1997), 2 stranded loggerhead sea turtles with squamous cell carcinomas were submitted to the Veterinary Faculty, ULPGC. The first was a 6.5 kg juvenile female stranded in Gran Canaria (27°40' N, 15°20' W). The turtle had a curved carapace length and width of 33 and 31 cm respectively, and a straight carapace length and width of 29 and 28 cm respectively. After stranding, the turtle had been housed in an aquarium at the Wildlife Rehabilitation Center of Tafira, Gran Canaria. Physical examination had revealed anorexia and lethargy. Despite forcefeeding and intramuscular administration of antimicrobial enrofloxacin, the turtle died 1 wk after stranding. The second turtle was a 7.2 kg juvenile female found stranded dead in Fuerteventura (28°10' N, 14°20' W). This turtle had a curved carapace length and width of 34 and 33 cm respectively, and a straight carapace length and width of 31 and of 30 cm respectively.The gross postmortem examinations of both turtles were carried out using the protocol developed by Wolke & George (1981). Fecal specimens were processed following techniques described by Boch & Supperer (1982).Macroscopic lesions were recorded and tissue samples from all major organs were fixed in 10% neutral buffered formalin, embedded i...

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“…The tumor arising from the skin of the footpad, such as that detected in the captive Chaco eagle, is a unique presentation of SCCs in birds of prey. The most common body locations of SCCs in raptors include the flank, thigh, prefemoral region, ventral aspect of the wing, and oral cavity [11,15,16]. Moreover, SCCs on the sole of feet are also rare in other birds [1,14].…”

mentioning

confidence: 99%

“…Metastases were remarkable in the organs within the coelomic cavity of the crowned solitary eagle with SCC in the footpad. Most skin SSCs are not metastatic in raptors [3,6]; however, metastases of an oral SCC has occurred in the lung and bones of a Montagu's harrier [15]. In general, SCCs are locally invasive, and metastases are rare in birds [11,12].…”

mentioning

confidence: 99%

Squamous cell carcinoma of the footpad with systemic metastasis in a captive crowned solitary eagle (<i>Buteogallus coronatus</i>)

Rocha

Wilson

Sousa

et al. 2020

The Journal of Veterinary Medical Science

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Squamous cell carcinoma of the footpad with systemic metastasis in a captive crowned solitary eagle (Buteogallus coronatus) Abstract: Squamous cell carcinomas (SCC) are one of the most common tumors of the tegument that can have a misdiagnosis of chronic skin wounds. An adult captive crowned solitary eagle presented an indolent wound-like ulcer on the footpad and a fatal outcome. An infiltrating tumoral mass in the foot and multiple tumoral metastatic nodules in visceral organs were detected. The neoplasm was composed of atypical squamous cells with strong positivity for cytokeratin, "keratin pearl" structures, and marked invasion of tissues confirming a diagnosis of metastatic SCC. This might be the first report of an SSC with metastasis on the footpad in a captive Chaco eagle, which is one of the endangered species of birds of prey.

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Metastatic Oral Squamous Cell Carcinoma in a Montagu's Harrier (Circus Pigargus)

Cited by 20 publications

References 7 publications

Management of a Cutaneous Squamous Cell Carcinoma in an American Flamingo (Phoenicopterus ruber)

Management of a Cutaneous Squamous Cell Carcinoma in an American Flamingo (Phoenicopterus ruber)

Metastatic squamous cell carcinoma in two loggerhead sea turtles Caretta caretta

Squamous cell carcinoma of the footpad with systemic metastasis in a captive crowned solitary eagle (<i>Buteogallus coronatus</i>)

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