Metastatic Neoplasm Presenting as Primary Cancer of the Breast: Case Reports

Dardick, Larry; O'Neill, Edward J.; Saxena, Naresh C.; Corner, Thomas P.; P, Bormanis; Weinstein, Eugene C.

doi:10.1093/milmed/149.7.411

Cited by 8 publications

(2 citation statements)

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“…However other authors believe that SCNC is a distinct type of breast carcinoma different from the usual types of carcinoma, with variable degrees of neuroendocrine differentiation which carries worse prognosis (2,6). Some authors claim that the presence of an in situ carcinoma, with areas of ductal, lobular, or papillary differentiation within the breast is highly suggestive of a primary breast rather than a metastatic tumor (6,8,9), however this criterion was not met in most published descriptions of this rare tumor (10).…”

Section: Discussionmentioning

confidence: 99%

An Unusual Case of Primary Small Cell Neuroendocrine Carcinoma of the Breast

et al. 2010

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Primary small cell neuroendocrine carcinoma of breast is a rare entity, with only case reports in literature. Histologically, these tumors are similar to small cell carcinoma of the lung with some evidence of ductal carcinoma-in-situ with areas of ductal, lobular, or papillary differentiation. Immunoreactivity for neuroendocrine markers is present in two thirds of cases, while 33-50% are positive for estrogen receptor or progesterone receptor. Her2/neu expression has not been reported in small cell carcinoma of the breast. Here we are presenting 53-year-old women with locally advanced primary small cell neuroendocrine carcinoma of breast. We will discuss clinicopathological findings, treatment options, prognosis and review of the literature on primary small cell carcinoma of breast.

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Section: Discussionmentioning

confidence: 99%

An Unusual Case of Primary Small Cell Neuroendocrine Carcinoma of the Breast

et al. 2010

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“…As in other studies, the most common extramammary primaries in women were, in order of decreasing frequency: melanoma, lymphoma, lung carcinoma, ovarian carcinoma and soft tissue sarcoma, followed by gastrointestinal and genitourinary primaries. Studies have shown that melanoma and prostate cancer are the most common extramammary cancer sites reported in men [33][34][35]101,102].…”

Section: Review -Masoodmentioning

confidence: 99%

Characteristics of Systemic Diseases in the Breast: Clinical, Imaging and Pathologic Features

Masood

2012

Womens Health (Lond Engl)

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Despite tremendous efforts placed on advances in diagnosis and treatment of the spectrum of breast disease, the impact of systemic diseases on the breast has remained under recognized. Distinction between a variety of benign breast diseases versus those that are manifestations of a systemic disease is critically important for appropriate treatment planning and follow-up of patients. This article is designed to provide an overview of different systemic diseases that can present as a breast lesion. Attempts are made to highlight the significance of the distinction between benign breast disease versus benign conditions that present as the result of a systemic disease. Naturally, distinction between any benign condition versus breast carcinoma is a part of the evaluation process.

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Overview of Metastatic Spreading

Kaiser¹

1989

Metastasis / Dissemination

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Metastatic Neoplasm Presenting as Primary Cancer of the Breast: Case Reports

Cited by 8 publications

References 0 publications

An Unusual Case of Primary Small Cell Neuroendocrine Carcinoma of the Breast

An Unusual Case of Primary Small Cell Neuroendocrine Carcinoma of the Breast

Characteristics of Systemic Diseases in the Breast: Clinical, Imaging and Pathologic Features

Overview of Metastatic Spreading

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