Metastatic intraocular hemangiopericytoma in a dog

Abstract

A 10-year-old Labrador Retriever who had been undergoing therapy for a recurrent hemangiopericytoma of the right flank presented to the Kansas State University Ophthalmology service for evaluation of a painful left eye. Examination revealed secondary glaucoma and irreversible blindness of the affected eye and multifocal chorioretinal lesions in the fellow eye. Therapeutic and diagnostic enucleation of the left eye was performed and histopathologic examination demonstrated the presence of a presumed metastatic spindle cell sarcoma. Further immunohistochemical staining confirmed the intraocular neoplasia to be metastatic spread from the previously removed flank mass. Rapid progression in size and number of chorioretinal lesions in the right eye was noted in the post-operative period until the patient was euthanized one month after surgery. This case report is the first to document intraocular metastasis of hemangiopericytoma in a veterinary patient.

Bilateral ocular metastatic melanoma of unknown primary (MUP) in a dog

“…Ocular metastasis is a differential diagnosis for canine uveitis and occurs infrequently in dogs despite an abundant blood supply to the uveal layer 1 2. Round cell tumours, specifically lymphoma and histiocytic sarcoma, are the most common tumours to secondarily involve the canine eye,3 4 whereas metastasis of malignant melanoma and various other tumour types are uncommonly reported 5–11. Ophthalmic presentation is unilateral or bilateral and is similar in all types of metastatic tumour, including visual deficits, ocular discomfort, uveitis, iris mass lesions and secondary glaucoma 3–11.…”