Metastatic Crohn's Disease

Hackzell-Bradley, Maria

doi:10.1001/archderm.1996.03890320076012

Cited by 55 publications

(12 citation statements)

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“…Clinically, most reports describe papules, plaques and nodules that may ulcerate. Histopathologically there is a wide range of findings; however, in the majority of cases the main changes are: (i) non‐caseating granulomatous inflammation involving predominantly the dermis; (ii) perivascular granulomas with or with vasculitis; and (iii) necrobiotic changes in the dermis 3,4 …”

Section: Discussionmentioning

confidence: 99%

Acute Crohn’s colitis with lobular panniculitis – metastatic Crohn’s?

Yosipovitch

Hodak²,

Feinmesser

et al. 2000

Acad Dermatol Venereol

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One of the common lesions in Crohn's colitis is erythema nodosum, a septal panniculitis that may appear before diagnosis or in conjunction with flare up. We report a case of Crohn's colitis where the presenting sign was neutrophilic lobular panniculitis with few granulomas. The possibility that this case represents a forme fruste of metastatic Crohn's is suggested. As skin biopsies are not usually performed by gastroenterologists in erythema nodosum-like skin lesions in Crohn's patients it may well be that the incidence of lobular panniculitis is higher than reported in the literature.

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Section: Discussionmentioning

confidence: 99%

Acute Crohn’s colitis with lobular panniculitis – metastatic Crohn’s?

Yosipovitch

Hodak²,

Feinmesser

et al. 2000

Acad Dermatol Venereol

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“…Genital MCD may be the most common presentation in young persons. 3,5,6,8 This case is unusual in that it initially presented as erythematous nodular lesions on the scalp.…”

Section: Reportmentioning

confidence: 94%

“…MCD can be contiguous or noncontiguous with the GI tract. MCD involves the presence of cutaneous granuloma that are distant from the intestinal lesions, and usually observed in colonic Crohn's disease 4–6 . The mechanisms of MCD remain unclear.…”

Section: Reportmentioning

confidence: 99%

“…MCD involves the presence of cutaneous granuloma that are distant from the intestinal lesions, and usually observed in colonic Crohn's disease. [4][5][6] The mechanisms of MCD remain unclear. Burgdorf and Orkin suggested that immune complexes in the skin could be partly responsible for the granulamatous reaction.…”

Section: Reportmentioning

confidence: 99%

“…Nutritional changes associated with malabsorption include acquired zinc deficiency with an acrodermatitis enteropathica-like eruption, pellagra and pernicious anaemia. 1,3,5,6 Linear growth retardation is a major complication of Crohn's disease occurring in children. It is related both to undernutrition and to direct effects of the inflammatory process on the growth axis.…”

Section: Reportmentioning

confidence: 99%

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