Metastatic Colorectal Cancer to the Small Bowel—an Uncommon Cause of Obscure GI Bleeding: a Three-Case Experience with Review of the Literature

Thoma, Matthew N.; Saiyed, Salim M.; Charles, Roger

doi:10.1007/s12029-010-9185-5

Cited by 9 publications

(5 citation statements)

References 14 publications

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“…This case was considered to be hematogenous metastasis because it involved multiple lung metastases, a portal vein tumor thrombus (VP2) and no peritoneal dissemination or direct invasion by CT. Endoscopic findings of gastrointestinal metastasis from HCC vary, but include raised and centrally ulcerated lesions, polypoid tumors and submucosal tumors [2, 4]. Several reported cases of small bowel metastasis have been diagnosed using CE and DBE [5, 6, 7, 8, 9, 10, 11]. However, only one case of small bowel metastasis from HCC diagnosed by DBE has been reported [5].…”

Section: Discussionmentioning

confidence: 99%

Small Bowel Metastasis of Hepatocellular Carcinoma Detected by Capsule Endoscopy

Igawa

Oka

Tanaka

et al. 2013

Case Rep Gastroenterol

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We report a rare case of metastasis of hepatocellular carcinoma (HCC) to the small bowel that presented as a pedunculated epithelial polyp. A 60-year-old man with liver cirrhosis type B was treated for HCC (stage IVb) at our hospital. He had been admitted for melena and anemia. Capsule endoscopy was performed in this patient with obscure gastrointestinal bleeding. It showed a polypoid lesion with bleeding in the ileum. Double-balloon endoscopy was performed. The lesion was determined to be a pedunculated polyp in the ileum. Histological examination of biopsy specimens showed tumor cells resembling HCC. We performed endoscopic mucosal resection for the lesion by double-balloon endoscopy to prevent bleeding from the tumor. The patient had no melena or anemia and his condition improved after endoscopic mucosal resection. However, he died of liver failure 2 months later.

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Section: Discussionmentioning

confidence: 99%

Small Bowel Metastasis of Hepatocellular Carcinoma Detected by Capsule Endoscopy

Igawa

Oka

Tanaka

et al. 2013

Case Rep Gastroenterol

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“…Metastatic involvement of small intestine is typically associated with a poor prognosis [12]. Metastatic tumors are found owing to the remarkable symptoms, and resection of the tumor is often required to afford symptomatic relief.…”

Section: Discussionmentioning

confidence: 99%

Hematogenous intestinal metastases from sigmoid colon cancer presenting as iliopsoas abscess and bowel obstruction

et al. 2019

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Intestinal metastases from colorectal cancer typically occur by intraperitoneal spread, whereas those occurring via hematogenous route are exceedingly rare. We report a case of intestinal metastases from sigmoid colon cancer that presented as iliopsoas abscess and ileus. A 78-year-old man who had undergone sigmoidectomy for sigmoid colon cancer 5 years ago was referred to our hospital with recurrent ileus and fever. Abdominal computed tomography showed a left iliopsoas abscess and a mass near the abscess that had ostensibly caused ileus. The patient underwent segmental resection of the jejunum including the mass. Histopathological examination of the resected specimen revealed moderately differentiated adenocarcinoma proliferating mainly in the submucosal and muscular layers, which was pathologically identical to the colon cancer resected 5 years ago. He died 18 months after the surgery because of liver metastases. This case report highlights the delayed occurrence of colorectal metastases at unusual sites, such as the small bowel, more than 5 years after the resection of the primary cancer. Intestinal metastases should be considered in patients with a history of colon cancer, particularly in those with recurrent ileus or abdominal abscess with no obvious cause.

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“…The incidence of metastatic colorectal cancer to the small intestine is about 6%. 3 However, metastatic primary appendiceal cancer to the GI tract is rare, and only two cases of gastric metastases have been reported. 4 5 However, small bowel metastases caused by primary appendiceal cancer have never been reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

Capsule retention caused by duodenal metastases from primary appendiceal adenocarcinoma

Chou

Cheng

2017

Intest Res

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Metastatic small bowel cancers are extremely rare in clinical practice. Primary appendiceal adenocarcinoma with gastrointestinal metastasis is seldom reported in the literature. Here, we describe the case of an 80-year-old male patient with primary appendiceal adenocarcinoma, who presented to China Medical University Hospital with mid-gastrointestinal tract bleeding. Capsule endoscopy revealed stenotic bowel lumen, but the capsule was retained in the distal duodenum. Double-balloon enteroscopy demonstrated erosive and erythematous mucosa in the region of capsule retention. The retained capsule was retrieved successfully by using an electrosurgical snare. Histological examination and immunohistochemical staining of the biopsy specimen from the duodenal lesion strongly supported the diagnosis of metastatic appendiceal adenocarcinoma.

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Metastatic Colorectal Cancer to the Small Bowel—an Uncommon Cause of Obscure GI Bleeding: a Three-Case Experience with Review of the Literature

Cited by 9 publications

References 14 publications

Small Bowel Metastasis of Hepatocellular Carcinoma Detected by Capsule Endoscopy

Small Bowel Metastasis of Hepatocellular Carcinoma Detected by Capsule Endoscopy

Hematogenous intestinal metastases from sigmoid colon cancer presenting as iliopsoas abscess and bowel obstruction

Capsule retention caused by duodenal metastases from primary appendiceal adenocarcinoma

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