Metastatic Adenocarcinoma to the Anterior Uvea and Increased Carcinoembryonic Antigen Levels

Diagnostic Procedures in Ophthalmology

“…[21] A few cases were reported on the use of aqueous sampling for cytology which led to the diagnosis of metastases masquerading as anterior uveitis. [79][80][81][82][83][84] Of patients undergoing diagnostic vitrectomy for uveitis of unknown cause, detection of metastasis from cytology results was rare in the literature, [11,85,86] with only one case reported in each of these series. In case reports of patients with the rare occurrence of tumors metastatic to the retina and vitreous, these conditions present as intermediate uveitis, vitreous hemorrhage, or retinal vasculitis with vitreous cytology and retinal biopsy assisting in diagnosis if no primary malignancy is identified.…”

Diagnostic Procedures in Ophthalmology

“…[21] A few cases were reported on the use of aqueous sampling for cytology which led to the diagnosis of metastases masquerading as anterior uveitis. [79][80][81][82][83][84] Of patients undergoing diagnostic vitrectomy for uveitis of unknown cause, detection of metastasis from cytology results was rare in the literature, [11,85,86] with only one case reported in each of these series. In case reports of patients with the rare occurrence of tumors metastatic to the retina and vitreous, these conditions present as intermediate uveitis, vitreous hemorrhage, or retinal vasculitis with vitreous cytology and retinal biopsy assisting in diagnosis if no primary malignancy is identified.…”

Iris metastasis: an unusual cause of anterior uveitis

“…Serum carcinoembryonic antigen can also be useful as it is raised (> 10 ng/ml) in tumours of endodermal origin but normal in patients with uveal melanoma. 6 Therapy is aimed at alleviating ocular symptoms. The indications are pain, uveitis, or glaucoma.…”

OPHTHALMIC MANIFESTATIONS OF SYSTEMIC NEOPLASIA: A review and report of 11 cases

“…These concepts have been emphasized recently in the literature. 48. 49 Lesions simulating metastases may occur in patients with known systemic ~a n c e r ,~' and therefore such non-metastatic disease in the eye needs to be excluded.…”

Diagnostic Procedures in Ophthalmology

“…[21] A few cases were reported on the use of aqueous sampling for cytology which led to the diagnosis of metastases masquerading as anterior uveitis. [79][80][81][82][83][84] Of patients undergoing diagnostic vitrectomy for uveitis of unknown cause, detection of metastasis from cytology results was rare in the literature, [11,85,86] with only one case reported in each of these series. In case reports of patients with the rare occurrence of tumors metastatic to the retina and vitreous, these conditions present as intermediate uveitis, vitreous hemorrhage, or retinal vasculitis with vitreous cytology and retinal biopsy assisting in diagnosis if no primary malignancy is identified.…”

Iris metastasis: an unusual cause of anterior uveitis

“…Serum carcinoembryonic antigen can also be useful as it is raised (> 10 ng/ml) in tumours of endodermal origin but normal in patients with uveal melanoma. 6 Therapy is aimed at alleviating ocular symptoms. The indications are pain, uveitis, or glaucoma.…”

OPHTHALMIC MANIFESTATIONS OF SYSTEMIC NEOPLASIA: A review and report of 11 cases

“…These concepts have been emphasized recently in the literature. 48. 49 Lesions simulating metastases may occur in patients with known systemic ~a n c e r ,~' and therefore such non-metastatic disease in the eye needs to be excluded.…”

Diagnostic Procedures in Ophthalmology

“…[21] A few cases were reported on the use of aqueous sampling for cytology which led to the diagnosis of metastases masquerading as anterior uveitis. [79][80][81][82][83][84] Of patients undergoing diagnostic vitrectomy for uveitis of unknown cause, detection of metastasis from cytology results was rare in the literature, [11,85,86] with only one case reported in each of these series. In case reports of patients with the rare occurrence of tumors metastatic to the retina and vitreous, these conditions present as intermediate uveitis, vitreous hemorrhage, or retinal vasculitis with vitreous cytology and retinal biopsy assisting in diagnosis if no primary malignancy is identified.…”

Iris metastasis: an unusual cause of anterior uveitis

“…Serum carcinoembryonic antigen can also be useful as it is raised (> 10 ng/ml) in tumours of endodermal origin but normal in patients with uveal melanoma. 6 Therapy is aimed at alleviating ocular symptoms. The indications are pain, uveitis, or glaucoma.…”

OPHTHALMIC MANIFESTATIONS OF SYSTEMIC NEOPLASIA: A review and report of 11 cases

“…These concepts have been emphasized recently in the literature. 48. 49 Lesions simulating metastases may occur in patients with known systemic ~a n c e r ,~' and therefore such non-metastatic disease in the eye needs to be excluded.…”