Metastatic adenocarcinoma mimicking hidradenitis suppurativa

Cutaneous Malignancy in Hidradenitis Suppurativa

“…Punch biopsy revealed metastatic adenocarcinoma with positive CK7 and CDX2, consistent with a metastatic GI/pancreaticobiliary adenocarcinoma. 4 It is important to note that when PET-CT imaging for cancer staging is performed, an increased uptake can be seen in inflammatory lesions of HS, as was the case with our patient. 5 This should not be misinterpreted because metastatic disease and clinical correlation is necessary.…”

“…Punch biopsy revealed metastatic adenocarcinoma with positive CK7 and CDX2, consistent with a metastatic GI/pancreaticobiliary adenocarcinoma. 4…”

The Role of FDG-PET in the Evaluation of Hidradenitis Suppurativa: A Systematic Review

“…Five articles featured case reports on the incidental detection of HS using FDG-PET scans while investigating malignant metastases. These case reports emphasized the capacity of FDG-PET scans to detect HS and demonstrated that detected lesions require further evaluation through biopsy to exclude occult malignancy [24,[33][34][35][36]. The last two articles comprised comprehensive reviews on the usefulness of various radiological techniques in diagnosing and managing HS.…”

“…An FDG-PET scan revealed that the patient's exophytic red nodules in his right axilla were metastases of adenocarcinoma, later confirmed through biopsy. This marked the first study to detect cutaneous metastases initially thought to be HS [35], highlighting the utility of FDG-PET scans in differentiating between HS and cutaneous malignancy.…”

“…Baig 2022 [35] 56-year-old Hispanic man with a history of adenocarcinoma and hidradenitis suppurativa…”