Metastasizing Bronchopulmonary Leiomyosarcoma

Abstract

An otherwise healthy 55-year-old female, nonsmoker, was seen in pulmonary consultation for progressively worsening shortness of breath. She had undergone a complete hysterectomy 7 years prior for bleeding leiomyomas. On presentation, her initial chest X-ray showed a large right-sided pleural effusion with multiple pulmonary nodules. Two thoracenteses failed to reveal any cytologic abnormalities. Bronchoscopy revealed smooth, round, endobronchial lesions. Histologic examination showed features consistent with leiomyosarcoma. We present a rare case of a patient that initially had possible leiomyomas of the uterus surgically removed and years later presented with bronchopulmonary leiomyosarcoma.

Pleural Effusion with Mediastinal and Hemidiaphragm Mass Effect: A Case Report

“…Leiomyosarcomas comprise 0.5% of lung neoplasms and can seed the lungs, remaining dormant for many years [3][4]. While the patient exhibited cardiorespiratory collapse secondary to mediastinal shift and left lung collapse, pulmonary metastases may also demonstrate left atrial extension, causing heart failure and pulmonary hypertension.…”