Metastasis to deep obturator and para-aortic lymph nodes in 649 patients with cervical carcinoma

Huang, Hui-Qiang; Liu, Jihong; Li, Yuhong; Wan, Ting; Yu, Feng; Li, Z.; Huang, Qunxiong

doi:10.1016/j.ejso.2011.08.128

Cited by 27 publications

(48 citation statements)

References 12 publications

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“…75 Para-Aortic Lymph Node Assessment Studies of the incidence and distribution of lymph node metastases in women with stage IB to IIB cervical cancers suggest that para-aortic lymph node involvement is closely tied to the presence of pelvic lymph node metastases, larger primary tumor size (>2 cm), and metastasis to the common iliac nodes. 94,95 Analysis of outcomes data from 555 women who participated in GOG trials (GOG 85, GOG 120, and GOG 165) revealed a more positive prognosis for patients who underwent surgical exclusion of para-aortic lymph node involvement versus those who underwent radiographic determination of para-aortic node involvement. 4 One study examined the efficacy of extending the radiation therapy (RT) field to the para-aortic region in patients with para-aortic lymph node involvement, and showed therapeutic benefit especially in patients with small-vol- ume nodal disease.…”

Section: Sentinel Lymph Node Mappingmentioning

confidence: 99%

Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology

Koh¹,

Abu‐Rustum²,

Bean³

et al. 2019

J Natl Compr Canc Netw

742

638

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Cervical cancer is a malignant epithelial tumor that forms in the uterine cervix. Most cases of cervical cancer are preventable through human papilloma virus (HPV) vaccination, routine screening, and treatment of precancerous lesions. However, due to inadequate screening protocols in many regions of the world, cervical cancer remains the fourth-most common cancer in women globally. The complete NCCN Guidelines for Cervical Cancer provide recommendations for the diagnosis, evaluation, and treatment of cervical cancer. This manuscript discusses guiding principles for the workup, staging, and treatment of early stage and locally advanced cervical cancer, as well as evidence for these recommendations. For recommendations regarding treatment of recurrent or metastatic disease, please see the full guidelines on NCCN.org.

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Section: Sentinel Lymph Node Mappingmentioning

confidence: 99%

Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology

Koh¹,

Abu‐Rustum²,

Bean³

et al. 2019

J Natl Compr Canc Netw

742

638

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“…They proposed that after dissection of superficial obturator lymph nodes, additional lymph nodes might appear in fatty areas below the obturator nerve to which metastasis might occur in cervical carcinoma patients. In the same study, mean DOLN count was 4 (range 2-8) and metastasis was seen in 3 (1.3%) of 225 patients (Panici et al 1992 (Huang et al 2011). In the present study, we performed lymphadenectomy by dissecting the lymph nodes accompanied by pelvic vasculature as described in previous studies (Mayer et al 1992;Hacker et al 1995;Mariani et al 2006).…”

Section: Discussionmentioning

confidence: 88%

“…There are not any statistically significant differences between DOLN dissected and non-dissected groups in complication rates, mean operation times, mean units of blood transfused and duration of hospitalisation. Two publications in the literature describe DOLN (Panici et al 1992;Huang et al 2011). These 2 publications describe only the count of dissected lymph nodes, but neither complication rates nor operation times are described in these studies.…”

Section: Discussionmentioning

confidence: 97%

Deep obturator lymph node dissection in gynaecological cancer patients: Is it feasible and useful?

Padak¹,

Kasap

Yetimalar

et al. 2016

Journal of Obstetrics and Gynaecology

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TurkeyOur aim was to investigate the feasibility and outcomes of deep obturator lymph node (DOLN) dissection in gynaecological cancer patients. A prospective study included 62 patients with a diagnosis of ovarian, endometrial or cervical cancer who underwent surgery. In the study group, 36 patients underwent obturator lymph node dissection above and under the obturator nerve, while 26 control group patients underwent routine obturator lymph node dissection above the obturator nerve. Groups were compared with respect to dissected lymph node count, intraoperative characteristics and early postoperative complications. Total lymph node count in the DOLN dissected group was greater than that in the control group, and the difference was statistically significant. No statistically significant difference was found between the groups, regarding postoperative complications and intraoperative characteristics. The total number of lymph nodes dissected by using DOLN dissection increased without an increase in intra-and postoperative complications in gynaecological cancer patients.

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“…Studies of the incidence and distribution of lymph node metastases in women with stage IB to IIB cervical cancers suggest that para-aortic lymph node involvement is closely tied to the presence of pelvic lymph node metastases, larger primary tumor size (>2cm), and metastasis to the common iliac nodes. 107,108 Analysis of outcomes data from 555 women who participated in Gynecologic Oncology Group (GOG) trials (GOG 85, GOG 120, and GOG 165) revealed a more positive prognosis for patients who underwent surgical exclusion of para-aortic lymph node involvement versus those who underwent radiographic determination of para-aortic node involvement. 29 One study examined the efficacy of extending the radiation therapy (RT) field to the para-aortic region in patients with para-aortic lymph node involvement, and showed therapeutic benefit especially in patients with small-volume nodal disease.…”

Section: Para-aortic Lymph Node Assessmentmentioning

confidence: 99%

End of the minimal invasion surgery in cervical cancer?

Hernández¹

2018

Cancer Rep Rev

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NCCN believes that the best management for any patient with cancer is in a clinical trial. Participation in clinical trials is especially encouraged. To find clinical trials online at NCCN Member Institutions, click here: nccn.org/clinical_trials/physician.html. NCCN Categories of Evidence and Consensus: All recommendations are category 2A unless otherwise indicated. See NCCN Categories of Evidence and Consensus.

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Metastasis to deep obturator and para-aortic lymph nodes in 649 patients with cervical carcinoma

Cited by 27 publications

References 12 publications

Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology

Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology

Deep obturator lymph node dissection in gynaecological cancer patients: Is it feasible and useful?

End of the minimal invasion surgery in cervical cancer?

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