Metastasis of Dermatofibrosarcoma from the Abdominal Wall to the Thyroid Gland: Case Report

Kréze, A; Zápotocká, Andrea; Urbanec, Tomas; Koskuba, Jiří; Pura, Mikuláš; Vitek, P.; Praženica, Pavol; Traboulsi, Eva

doi:10.1155/2012/659654

Cited by 7 publications

(2 citation statements)

References 22 publications

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“…Until 2012, only about 20 cases of sarcomas metastatic to the thyroid gland have been reported in the literature,11 12 with one coming from malignant phyllodes tumour associated with metastases to other organs 7. Since then, thyroid metastasis from malignant fibrous histiocytoma,10 dermatofibrosarcoma,12 rhabdomyosarcoma13 and cardiac sarcoma14 have been reported. Moreover, of 28 documented cases in the literature of tumour-to-tumour metastasis to thyroid neoplasms, such as follicular adenomas and papillary carcinomas, only 1 came from a malignant phyllodes tumour and only 15% (3/20 cases available for determination) were isolated to the thyroid neoplasm,15 which is another (the third) unusual angle of the case presented, that of the normal, rather than neoplastic, thyroid being the only site of metastasis, as proven by the negative bone/SPECT CT scan.…”

Section: Discussionmentioning

confidence: 99%

Isolated thyroid metastasis from benign phyllodes tumour

Kho

Abelardo

2018

BMJ Case Reports

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We present a rare and interesting case of a 35-year-old woman who initially underwent an uneventful wide excision for a 13 cm left benign phyllodes tumour. She then noted a slowly growing left thyroid nodule 8 months postsurgery which on thyroidectomy 4 years later was shown to be a 6.9cm isolated thyroid metastasis from the phyllodes tumour. As this may be the first reported such case in the literature, implications on histological classification, predictive factors for disease progression, mechanisms of metastasis, and evaluation, management and surveillance of benign phyllodes tumours and thyroid nodule/s with a history of phyllodes tumour can thus be significantly impacted.

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Section: Discussionmentioning

confidence: 99%

Isolated thyroid metastasis from benign phyllodes tumour

Kho

Abelardo

2018

BMJ Case Reports

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“…In the scientific literature, many cases of metastatic tumors in the thyroid have been published as case reports describing the pitfalls of individual case diagnosis supported by a literature overview, stressing the specific context of the more frequent primary malignancies or the reporting a rare malignancy metastasizing to the thyroid [11,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31]. Meta-analyses are available for the most frequent primary malignancies [32,33].…”

Section: Discussionmentioning

confidence: 99%

Secondary or Second Primary Malignancy in the Thyroid? Metastatic Tumors Suggested Clinically: A Differential Diagnostic Task

Dušková

Přeučil²,

Svobodová³

et al. 2014

Acta Cytologica

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Objective: To describe the algorithms employed to explore the suggestion or consideration of metastatic malignancy in the thyroid. Study Design: Thirty-seven cases with a history of malignancy (n = 21) and/or uncommon fine-needle aspiration biopsy (FNAB) findings (n = 37) were reviewed and reclassified according to The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). Results: The group was heterogeneous in terms of the final histopathology results: the suggested metastasis was confirmed in only half of the cases (11/21; 52.4%). Primary thyroid malignancies were mostly nondifferentiated, medullary, or rare. However, 3 papillary carcinomas (the less common variants) were also found. Finally, 5 out of 37 cases were surprisingly benign upon histopathological investigation (uncommon repair and fibrotizing Hashimoto thyroiditis). Conclusions: The metastatic nature of thyroid gland nodule(s) must be considered in cases of generalization of malignancy and/or uncommon FNAB findings. We must be as open-minded as possible from the outset. Additional techniques are helpful if available - cytoblock and immunocytochemistry can contribute substantially. Morphological comparisons with the previous malignancy are recommended whenever possible. To avoid overtreatment, cases without precise typing should not be classified as TBSRTC diagnostic category VI - malignant, but should remain in TBSRTC diagnostic category V - suspicious for malignancy. Repeated FNAB to enable additional techniques may be suggested.

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Rare case of metastatic liposarcoma to the thyroid gland and a review of the literature of metastatic sarcomas to the thyroid

et al. 2020

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Background Liposarcomas are the second most common type of soft tissue sarcomas. Typically, myxoid liposarcomas have a metastatic rate of 10%, usually involving the retroperitoneal space, abdomen, and spine. Metastasis to the thyroid is extremely rare. Design/Method A 62‐year‐old male with a history of metastatic myxoid liposarcoma in his right thigh presented to our clinic for evaluation of a thyroid nodule incidentally identified on a CT scan. A subsequent FNA biopsy was suggestive of a metastatic liposarcoma. Results The patient underwent a left thyroid lobectomy and final pathology confirmed a grade II/III metastatic myxoid liposarcoma that measured 3.3 cm. The patient tolerated the procedure well. Conclusions Our case highlights the role of a patient's medical history when evaluating thyroid nodules to optimize accurate diagnosis, as liposarcomas do not typically metastasize to the thyroid. We also provide an updated review of the literature on all cases of metastatic sarcomas to the thyroid.

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Metastasis of Dermatofibrosarcoma from the Abdominal Wall to the Thyroid Gland: Case Report

Cited by 7 publications

References 22 publications

Isolated thyroid metastasis from benign phyllodes tumour

Isolated thyroid metastasis from benign phyllodes tumour

Secondary or Second Primary Malignancy in the Thyroid? Metastatic Tumors Suggested Clinically: A Differential Diagnostic Task

Rare case of metastatic liposarcoma to the thyroid gland and a review of the literature of metastatic sarcomas to the thyroid

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