Metanephric adenoma in an 8-year-old child: case report and review of the literature

An Approach to Renal Masses in Pediatrics

“…[140][141][142] Patients can be asymptomatic 143,144 or can have signs and symptoms related to polycythemia, hypertension, hematuria, dysuria, flank or abdominal pain, or a palpable abdominal mass. 3 The lesion has radiologic similarities to RCC and WT, making preoperative diagnosis difficult. 141 MAs have been diagnosed by using ultrasound 141,145 or CT. 146 Histologic features of MA reveal small uniform epithelial cells of an acinar, tubular, glomeruloid, or papillary growth pattern with a high nuclear-to-cytoplasmic ratio.…”

“…1 They can be detected by a parent bathing or holding the child, during routine physical examination or screening of children with known clinical syndromes with predispositions to renal disease, 2 or incidentally during investigations for other intraabdominal processes. [3][4][5] The key challenge is distinguishing malignant neoplasms from benign masses. A thorough understanding of the profile of common renal masses in children, as well as their associated clinical and imaging features, can facilitate accurate preoperative diagnosis and optimize patient care.…”

Metanephric adenoma with diffuse calcifications: A case report

“…For example, the degree of enhancement of clear cell renal cell carcinoma is commonly higher than that of the renal cortex (17). These findings indicate that it may be relatively simple to distinguish between metanephric adenoma and tumors with a rich blood supply on the basis of differences in enhancement (18). For example, metanephric adenoma, collecting duct carcinaoma, chromophobe renal cell carcinoma and renal lymphoma are hypovascular on enhanced CT imaging compared with renal parenchyma.…”

CT and ultrasound findings of metanephric adenoma: a report of two cases and literature review

“…Hyperechogenicity on ultrasound is associated with the presence of psammomatous calcifications and interfaces caused by numerous tubules [5,7]. However, hypoechoic or hypodense masses were reported on ultrasonography or on unenhanced CT, indicating cystic changes, necrosis or haemorrhage [5,11,12]. Our two MAs appeared as slightly hyperdense masses on unenhanced CT and as well-demarcated, round, hypovascular solid masses in relation to the adjacent renal parenchyma on contrast-enhanced CT with mild enhancement after intravenous (iv) administration with a contrast agent.…”

“…Until now it was thought to have a benign course. In the English language literature no more than 100 cases of MAs have been reported, and in only a few have the imaging findings been well illustrated [2][3][4][5][6][7][8][9][10][11][12][13]. We report two cases of MA in a 17-year-old and a 30-year-old female and describe their appearances on CT and ultrasonography.…”