Metameric representations on optimization of nano particle cancer treatment

Tsompanas, Michail‐Antisthenis; Bull, Larry; Adamatzky, Andrew; Balaz, Igor

doi:10.1016/j.bbe.2021.02.002

Cited by 5 publications

(1 citation statement)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Evolutionary methodologies are employed to discover possible morphologies as it was proved that they can overpower human designers' capacity. An important meta-parameter in evolutionary methodologies is the representation of possible solutions (Ryerkerk et al, 2017;Tsompanas et al, 2021). Its choice mainly depends on the problem, while the level of advantages may vary.…”

Section: Introductionmentioning

confidence: 99%

Outline of an evolutionary morphology generator towards the modular design of a biohybrid catheter

Tsompanas,

Balaz

2024

Front. Robot. AI

Self Cite

View full text Add to dashboard Cite

Biohybrid machines (BHMs) are an amalgam of actuators composed of living cells with synthetic materials. They are engineered in order to improve autonomy, adaptability and energy efficiency beyond what conventional robots can offer. However, designing these machines is no trivial task for humans, provided the field’s short history and, thus, the limited experience and expertise on designing and controlling similar entities, such as soft robots. To unveil the advantages of BHMs, we propose to overcome the hindrances of their design process by developing a modular modeling and simulation framework for the digital design of BHMs that incorporates Artificial Intelligence powered algorithms. Here, we present the initial workings of the first module in an exemplar framework, namely, an evolutionary morphology generator. As proof-of-principle for this project, we use the scenario of developing a biohybrid catheter as a medical device capable of arriving to hard-to-reach regions of the human body to release drugs. We study the automatically generated morphology of actuators that will enable the functionality of that catheter. The primary results presented here enforced the update of the methodology used, in order to better depict the problem under study, while also provided insights for the future versions of the software module.

show abstract

Section: Introductionmentioning

confidence: 99%