Abstract:Aim: Matrix metalloproteinases, particularly MMP-2 and MMP-9, are the active factors influencing the structure and properties of the extracellular matrix. This effect is enhanced in metastasis. Hence, it is necessary to enrich the knowledge of the relation between the accumulation and distribution of the enzymes in cells and the intensity of their secretion.
Material/Methods: The study was conducted on three cell lines of dermal origin: normal line of human dermal fibroblasts (NHDF) and two melanoma lines (BM … Show more
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