Metalloproteinases and Spontaneous Coronary Artery Dissection Relationships: A Systematic Review

Abstract

Background: Spontaneous coronary artery dissection (SCAD) may predict fibromuscular dysplasia (FD) in lean Caucasian women, aged 15-50, with no prior history. There is a marked predominance in females with 75.0 to 100.0% of the cases. Objective: This study undertook a meta-analysis of matrix metalloproteinases 2 and 9 actions and inhibitions in the context of fibromuscular dysplasia and subsequent spontaneous coronary artery dissection. Methods: The literary search criteria used the Mesh Terms cited in the "Search strategies" section. One hundred and four papers submitted for eligibility analysis were collated, twenty-six studies were selected. The review protocol was based on the criteria of literary search with the use of mesh terms in the main databases such as Pubmed, Medline, Bireme, EBSCO, and Scielo. Conclusion: The patient was diagnosed with this pathology based on a prior acute myocardial infarction and the presence of coronary http://mo.qingres.com Metalloproteinases as Predictors of Coronary Disease Sofia Braile Sabino et al.