Metallomics: An Essential Tool for the Study of Potential Antiparasitic Metallodrugs
Ignacio Machado,
Dinorah Gambino
Abstract:Metallomics is an emerging area of omics approaches that has grown enormously in the past few years. It integrates research related to metals in biological systems, in symbiosis with genomics and proteomics. These omics approaches can provide in-depth insights into the mechanisms of action of potential metallodrugs, including their physiological metabolism and their molecular targets. Herein, we review the most significant advances concerning cellular uptake and subcellular distribution assays of different pot… Show more
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