Metallic Nanoparticles from Natural Products as a Potential Anti-Cancer

Roy, Arpan Dutta; Varghese, Kessia K; Ghosh, Sayantan; Paul, Prolay; Mitra, Indrajit; Harikrishna, Adicherl; P, Pallavi; Maiti, Sourav

doi:10.47583/ijpsrr.2021.v67i01.028

Cited by 2 publications

(1 citation statement)

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“…Nowadays, nanoparticles are utilized in targeted drug delivery systems in order to increase the efficiency of chemical agents (antineoplastic drugs). Silver, gold, zinc, copper, iron oxide, titanium dioxide, cerium dioxide, and iron-platinum have achieved considerable attention in this field due to their small size and ability to cross biological membranes (Andleeb et al, 2021;Desai et al, 2021;Nikzamir et al, 2021;Roy et al, 2021).…”

Section: Biomedical Applications Of Capped Nanoparticlesmentioning

confidence: 99%

Role of Biogenic Capping Agents in the Synthesis of Metallic Nanoparticles and Evaluation of Their Therapeutic Potential

Sidhu

Verma

Kaushal

2022

Front. Nanotechnol.

142

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The biomedical properties of nanoparticles have been the area of focus for contemporary science; however, there are issues concerning their long-term toxicities. Recent trends in nanoparticle fabrication and surface manipulation, the use of distinctive biogenic capping agents, have allowed the preparation of nontoxic, surface-functionalized, and monodispersed nanoparticles for medical applications. These capping agents act as stabilizers or binding molecules that prevent agglomeration and steric hindrance, alter the biological activity and surface chemistry, and stabilize the interaction of nanoparticles within the preparation medium. Explicit features of nanoparticles are majorly ascribed to the capping present on their surface. The present review article is an attempt to compile distinctive biological capping agents deployed in the synthesis of metal nanoparticles along with the medical applications of these capped nanoparticles. First, this innovative review highlights the various biogenic capping agents, including biomolecules and biological extracts of plants and microorganisms. Next, the therapeutic applications of capped nanoparticles and the effect of biomolecules on the efficiency of the nanoparticles have been expounded. Finally, challenges and future directions on the use of biological capping agents have been concluded. The goal of the present review article is to provide a comprehensive report to researchers who are looking for alternative biological capping agents for the green synthesis of important metallic nanoparticles.

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Section: Biomedical Applications Of Capped Nanoparticlesmentioning

confidence: 99%