Metal–Organic Gel-Modulated Synthesis of Hierarchically Porous Molecularly Imprinted Polymers for Efficient Removal of Sildenafil from Water

Abstract

Molecularly imprinted polymers (MIPs) with high specific recognition capability are promising in environmental remediation. However, traditional MIPs usually show poor specific binding affinity toward templates in pure aqueous medium, thus greatly limiting their practical applications in wastewater treatment. Herein, we proposed a facile and versatile method to synthesize a water-compatible hierarchically porous MIP (HP-MIP), in which a metal–organic gel (MOG) was formed by in situ assembly and acted as a removable structural modulator. Remarkably, the integration of the MOG modulator and template imprinting defects significantly improved the specific template binding affinity of HP-MIP in water. The adsorption behavior of HP-MIP fitted well with the heterogeneous Freundlich isotherm, suggesting that HP-MIP possessed greater site heterogeneity to sildenafil than HP-NIP, which confirmed the efficiency of HP-MIP for the removal of sildenafil from water. This approach provides an important pathway to prepare water-compatible porous MIP for efficient removal of highly toxic organic pollutants from wastewater.

Ultrathin P(NDI2OD‐T2) Films with High Electron Mobility in Both Bottom‐Gate and Top‐Gate Transistors

“…[ 11–13 ] It is worth mentioning that several film assembly methods were utilized in the past to form ultrathin OFET films. [ 14–18 ]…”

Hierarchical porous metal–organic gels and derived materials: from fundamentals to potential applications

“…For example, Sildenafil, a dangerous water pollutant was adsorbed from water by a hierarchically porous molecularly imprinted polymer (HP-MIPs) combined with a MOG based of the building blocks of MIL-100. 246 The MOG functions as a template and modulator, and is subsequently eluted from the composite by using acetic acid-methanol solution. By optimizing the ratio of Fe 3 O(H 2 O)(OH) and H 3 BTC content, a high Sildenafil adsorption capacity (17.8 mg g −1 ) was achieved for six cycles (Fig.…”

“…14d). 246 Copyright 2021, American Chemical Society. (c) Capacity of MOG (black bar) and FGO@MOG (red bar) for the adsorption of various oils and organic solvents.…”

Remediation of pharmaceuticals from contaminated water by molecularly imprinted polymers: a review

“…Due to hydrogen bonding between adsorbents and adsorbates and strong formation of stable complexes through the π–π interaction, this molecularly imprinted polymer displayed a better adsorption capacity of 90.91 mg g −1 towards naproxen compared to Fe 3 O 4 @ molecularly imprinted polymer. The details for the removal of the last studied non-steroidal anti-inflammatory (ketoprofen) (Madikizela et al 2018d ) and other drugs including sildenafil (Wan et al 2021 ), cyproheptadine (Cao et al 2021 ), amitriptyline (Cao et al 2021 ), desloratadine (Cao et al 2021 ), 8-chloroazatadine (Cao et al 2021 ), ketotifen fumarate (Cao et al 2021 ), praziquantel enantiomers (Do Nascimento et al 2019 ) are presented in Table 5 . The main inferences that can be drawn from Table 5 comprise: Molecularly imprinted materials have promising perspectives to be used in wastewater treatment due to their high selectivity towards target pharmaceuticals, compared to traditional adsorption materials The deployment of molecularly imprinted polymers for pharmaceutical removal may be more cost-effective compared to other removal techniques, such as photochemical, ozonolysis, or electro-decomposition methods because of co-existing organic matter in the water environment.…”