Metal–Organic Frameworks-Derived Material for Electrochemical Biosensors: Recent Applications and Prospects

Abstract

According to recent studies, interest in metal−organic frameworks (MOFs) and their derivatives are still developing in the field of electrochemical biosensing. This is due to their superior electrical conductivity, active surface area, and easier manufacturing procedures, when compared to other conventional materials. This study discusses current advances in the use of MOF nanoparticles as highly conductive substrates in electrochemical biosensing. Electrochemical biosensing is introduced by categorizing biosensors into enzyme and nonenzyme biosensors and for diagnosis of diseases is based on the application of the active detector. This study systematically compiled and analyzed the most recent published works in each category. This Review provides an overview of the many types of analyses, MOFs materials, and sensor performance. In this subject of science, broad concerns, difficulties, and future views are discussed.

Natural Polymer Encapsulated Zeolitic Imidazolate Framework-12 Composite toward Electrochemical Sensing of Antitumor Agent

“…Along with the conventional materials, there has recently been an upsurge interest in metal−organic framework (MOF) applications such as energy storage and conversion, smart responsive materials, electrocatalytic conversion, environment treatment, and biological detection. 19 As a result, modified electrodes made of MOFs combined with active species for electrochemical sensors are anticipated to be the best options for electroanalytical applications because they have much higher specific surface area than other traditional materials, allowing them to enhance catalytically active sites with a higher density, and also interconnected porosity makes it simple for the targeted analyte diffusion into these active sites. 20 Zeolitic imidazolate frameworks (ZIFs), a subclass of MOFs formed by the reaction of metal ions with organic ligands, have high stability, high crystallinity, large specific surface area, and regular structure.…”

“…To the detection of GA, numerous composites based on a diverse class of materials including carbon, metal oxides, and semiconductors have been reported so far. Along with the conventional materials, there has recently been an upsurge interest in metal–organic framework (MOF) applications such as energy storage and conversion, smart responsive materials, electrocatalytic conversion, environment treatment, and biological detection . As a result, modified electrodes made of MOFs combined with active species for electrochemical sensors are anticipated to be the best options for electroanalytical applications because they have much higher specific surface area than other traditional materials, allowing them to enhance catalytically active sites with a higher density, and also interconnected porosity makes it simple for the targeted analyte diffusion into these active sites .…”

Nanomaterial for Adjuvants Vaccine: Practical Applications and Prospects

“…Since the last decade of the 20th century, nanotechnology has been a field that is fast developing [5,[7][8]. To influence the performance of nanomaterials in biomedical applications, substantial advancements have been made in their nanoscale design and manipulation [9][10][11]. The parameters of high bioavailability, sustained, and regulated release patterns, imaging, targeting, and other factors can be met by the delivery of a variety of substances, including chemical medicines, proteins, and vaccinations.…”