Metal–organic frameworks: advanced tools for multicomponent reactions

Ghasemzadeh, Mohammad Ali; Mirhosseini‐Eshkevari, Boshra; Tavakoli, Mona; Zamani, Farzad

doi:10.1039/d0gc01767a

Cited by 88 publications

(43 citation statements)

References 134 publications

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“…The magnetic properties of this catalyst make it easy to recover, and it can be reused up to five times without significant loss in catalytic activity (96‐90 % yield). The reaction afforded a library of pyrroloacridin‐1‐(2 H )‐one derivatives (16 examples) in very good to excellent yields under the described eco‐friendly conditions (Scheme 131B) [262] . The same chemical framework was obtained using sustainable organocatalytic methodologies.…”

Section: Non‐oxindole Derivativesmentioning

confidence: 93%

Engaging Isatins in Multicomponent Reactions (MCRs) – Easy Access to Structural Diversity

Brandão

Marques

Carreiro

et al. 2021

The Chemical Record

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Multicomponent reactions (MCRs) are a valuable tool in diversity‐oriented synthesis. Its application to privileged structures is gaining relevance in the fields of organic and medicinal chemistry. Isatin, due to its unique reactivity, can undergo different MCRs, affording multiple interesting scaffolds, namely oxindole‐derivatives (including spirooxindoles, bis‐oxindoles and 3,3‐disubstituted oxindoles) and even, under certain conditions, ring‐opening reactions occur that leads to other heterocyclic compounds. Over the past few years, new methodologies have been described for the application of this important and easily available starting material in MCRs. In this review, we explore these novelties, displaying them according to the structure of the final products obtained.

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Section: Non‐oxindole Derivativesmentioning

confidence: 93%

Engaging Isatins in Multicomponent Reactions (MCRs) – Easy Access to Structural Diversity

Brandão

Marques

Carreiro

et al. 2021

The Chemical Record

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“…More broadly, these structures are defined as a highly porous three-dimensional network of metal cations connected by organic ligands (Furukawa et al, 2013). Applications of MOFs are extensively reported in the literature, and include environmental remediation via pollutant binding inside the MOF structure (Ejeromedoghene et al, 2020); supramolecular catalysis by encapsulating reactants (Ghasemzadeh et al, 2020); controlled crystallization via topological effects of MOF incorporation (Wang et al, 2020i), and a variety of other applications (Jones et al, 2018;Ding et al, 2020;Heo et al, 2020).…”

Section: Metal-organic Framework Pesticide Detectionmentioning

confidence: 99%

Fluorescence-Based Sensing of Pesticides Using Supramolecular Chemistry

Levine

2021

Front. Chem.

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The detection of pesticides in real-world environments is a high priority for a broad range of applications, including in areas of public health, environmental remediation, and agricultural sustainability. While many methods for pesticide detection currently exist, the use of supramolecular fluorescence-based methods has significant practical advantages. Herein, we will review the use of fluorescence-based pesticide detection methods, with a particular focus on supramolecular chemistry-based methods. Illustrative examples that show how such methods have achieved success in real-world environments are also included, as are areas highlighted for future research and development.

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“…Some multicomponent syntheses, however, may be efficiently conducted under heterogeneous conditions with effective catalytic system recovery [ 196 , 197 , 198 , 199 , 200 , 201 ]. Metal–organic frameworks (MOFs) are, however, active, programmable and recyclable catalysts successfully applied in MCR syntheses, as recently reviewed elsewhere [ 202 , 203 , 204 ]. This comparison reinforces the advantages of each newly developed catalytic cycle and highlights the importance of new approaches.…”

Section: Homogeneous and Heterogeneous Catalysismentioning

confidence: 99%

Catalytic Approaches to Multicomponent Reactions: A Critical Review and Perspectives on the Roles of Catalysis

2021

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In this review, we comprehensively describe catalyzed multicomponent reactions (MCRs) and the multiple roles of catalysis combined with key parameters to perform these transformations. Besides improving yields and shortening reaction times, catalysis is vital to achieving greener protocols and to furthering the MCR field of research. Considering that MCRs typically have two or more possible reaction pathways to explain the transformation, catalysis is essential for selecting a reaction route and avoiding byproduct formation. Key parameters, such as temperature, catalyst amounts and reagent quantities, were analyzed. Solvent effects, which are likely the most neglected topic in MCRs, as well as their combined roles with catalysis, are critically discussed. Stereocontrolled MCRs, rarely observed without the presence of a catalytic system, are also presented and discussed in this review. Perspectives on the use of catalytic systems for improved and greener MCRs are finally presented.

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Metal–organic frameworks: advanced tools for multicomponent reactions

Abstract: The increasing demand of simple, clean, and sustainable protocols for the preparation of complex organic molecules have continuously encouraged researchers to discover and design modern methodologies. Metal-catalyzed multicomponent reactions (MCRs)...

Cited by 88 publications

References 134 publications

Engaging Isatins in Multicomponent Reactions (MCRs) – Easy Access to Structural Diversity

Engaging Isatins in Multicomponent Reactions (MCRs) – Easy Access to Structural Diversity

Fluorescence-Based Sensing of Pesticides Using Supramolecular Chemistry

Catalytic Approaches to Multicomponent Reactions: A Critical Review and Perspectives on the Roles of Catalysis

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