Metal-Organic Framework-Based Stimuli-Responsive Polymers

Abstract

Metal-organic framework (MOF) based stimuli-responsive polymers (coordination polymers) exhibit reversible phase-transition behavior and demonstrate attractive properties that are capable of altering physical and/or chemical properties upon exposure to external stimuli, including pH, temperature, ions, etc., in a dynamic fashion. Thus, their conformational change can be imitated by the adsorption/desorption of target analytes (guest molecules), temperature or pressure changes, and electromagnetic field manipulation. MOF-based stimuli responsive polymers have received great attention due to their advanced optical properties and variety of applications. Herein, we summarized some recent progress on MOF-based stimuli-responsive polymers (SRPs) classified by physical and chemical responsiveness, including temperature, pressure, electricity, pH, metal ions, gases, alcohol and multi-targets.

Metal–organic frameworks (MOFs) as host materials for the enhanced delivery of biomacromolecular therapeutics

“…As such, stimuli-responsive MOFs are the ideal choice for the controlled release of biomacromolecules. 39,40 When stimulus-responsive MOFs are activated by specific intracellular triggers (e.g., acidic pH, reactive biospecies, ATP, etc. ), their host-guest architecture will collapse, thereby releasing the biomacromolecules in a controlled manner.…”

Thermoresponsive polymers as macromolecular coordination ligands: complexation-dependence of thermally induced aggregation in aqueous solution

“…31 Various systems based on macromolecular structures that combine metal complexation and responsiveness have been reported in the literature. 11,26,32,33 Inspired by this body of research, we have chosen to study dynamic structure formation of novel metal-polymer complexes based on metalcoordination motifs with thermoresponsive polymer ligands.…”

The role of phonons in switchable MOFs: a model material perspective

“…[7][8][9] The dynamics of these materials can be induced by the removal/incorporation of guest molecules, 10 pressure, photo-and thermostimulation. [11][12][13][14][15] Stimuli-responsive behaviour is accompanied by structural changes, which lead not only to a variation in porosity but also in characteristic vibrational ngerprints. [16][17][18][19] A thorough vibrational analysis provides important insight into elastic moduli, reecting the soness/ stiffness of switchable MOFs (compliance).…”