Metal–organic framework-based SERS sensing platforms for life and health detection

Ma, Lindong; Zhou, Xinyuan; Liu, Meihui; Li, Cancan; Wang, Tie

doi:10.1039/d3qm00471f

Cited by 7 publications

(1 citation statement)

References 117 publications

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“…[ 94,95 ] Benefiting from the inherent chemical enhancement characteristics and intense absorption ability, MOFs‐based SERS substrates could enhance the SERS signal obviously. [ 96,97 ] Wu et al. immobilized silver nanoparticles (AgNPs) on the surface of MIL‐101 (Fe) MOF via in situ growth approach to obtain the AgNPs@MOF SERS substrate ( Figure A).…”

Section: Mofs‐based Biosensors To Detect Vds Biomarkersmentioning

confidence: 99%

Bioactive Metal–Organic Frameworks as a Distinctive Platform to Diagnosis and Treat Vascular Diseases

Liu,

Li,

Wang

et al. 2024

Small

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Vascular diseases (VDs) pose the leading threat worldwide due to high morbidity and mortality. The detection of VDs is commonly dependent on individual signs, which limits the accuracy and timeliness of therapies, especially for asymptomatic patients in clinical management. Therefore, more effective early diagnosis and lesion‐targeted treatments remain a pressing clinical need. Metal–organic frameworks (MOFs) are porous crystalline materials formed by the coordination of inorganic metal ions and organic ligands. Due to their unique high specific surface area, structural flexibility, and functional versatility, MOFs are recognized as highly promising candidates for diagnostic and therapeutic applications in the field of VDs. In this review, the potential of MOFs to act as biosensors, contrast agents, artificial nanozymes, and multifunctional therapeutic agents in the diagnosis and treatment of VDs from the clinical perspective, highlighting the integration between clinical methods with MOFs is generalized. At the same time, multidisciplinary cooperation from chemistry, physics, biology, and medicine to promote the substantial commercial transformation of MOFs in tackling VDs is called for.

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Section: Mofs‐based Biosensors To Detect Vds Biomarkersmentioning

confidence: 99%

Bioactive Metal–Organic Frameworks as a Distinctive Platform to Diagnosis and Treat Vascular Diseases

Liu,

Li,

Wang

et al. 2024

Small

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Metal–Organic Frameworks in Surface Enhanced Raman Spectroscopy–Based Analysis of Volatile Organic Compounds

Allegretto,

Dostalek

2024

Advanced Science

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Volatile Organic Compounds (VOC) are a major class of environmental pollutants hazardous to human health, but also highly relevant in other fields including early disease diagnostics and organoleptic perception of aliments. Therefore, accurate analysis of VOC is essential, and a need for new analytical methods is witnessed for rapid on‐site detection without complex sample preparation. Surface‐Enhanced Raman Spectroscopy (SERS) offers a rapidly developing versatile analytical platform for the portable detection of chemical species. Nonetheless, the need for efficient docking of target analytes at the metallic surface significantly narrows the applicability of SERS. This limitation can be circumvented by interfacing the sensor surface with Metal–Organic Frameworks (MOF). These materials featuring chemical and structural versatility can efficiently pre‐concentrate low molecular weight species such as VOC through their ordered porous structure. This review presents recent trends in the development of MOF‐based SERS substrates with a focus on elucidating respective design rules for maximizing analytical performance. An overview of the status of the detection of harmful VOC is discussed in the context of industrial and environmental monitoring. In addition, a survey of the analysis of VOC biomarkers for medical diagnosis and emerging applications in aroma and flavor profiling is included.

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Nanopore/Nanocavity-Based Structures as Surface-Enhanced Raman Spectroscopy (SERS) Platforms

Heydaryan,

Aspoukeh,

Mehmandoust

et al. 2024

Plasmonics

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Metal–organic framework-based SERS sensing platforms for life and health detection

Abstract: Advancements in life and health detection technology can greatly improve early disease diagnosis and treatment options for patients. Surface Enhanced Raman Scattering (SERS) technology has become a preferred method for...

Cited by 7 publications

References 117 publications

Bioactive Metal–Organic Frameworks as a Distinctive Platform to Diagnosis and Treat Vascular Diseases

Bioactive Metal–Organic Frameworks as a Distinctive Platform to Diagnosis and Treat Vascular Diseases

Metal–Organic Frameworks in Surface Enhanced Raman Spectroscopy–Based Analysis of Volatile Organic Compounds

Nanopore/Nanocavity-Based Structures as Surface-Enhanced Raman Spectroscopy (SERS) Platforms

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