Metal-free cascade construction of C–C bonds by activation of inert C(sp³)–H bonds

Abstract

A new synthetic strategy for C-C bond formation has been developed via a free radical cascade process under metal-free conditions. Activation of inert C(sp(3))-H/elimination of SO2/C-C bond formation were achieved in sequence in this system.

Visible Light-Induced Radical Rearrangement to Construct C–C Bonds via an Intramolecular Aryl Migration/Desulfonylation Process

“…4 In addition, transition metalmediated reactions have also been applied to the field of aryl migration reactions. For example, Nevado's group has reported a copper-catalyzed aryl migration reaction by using Togni's reagent 5 to generate trifluoromethyl radical species.…”

Metal-free tandem oxidative C(sp3)–H bond functionalization of alkanes and dearomatization of N-phenyl-cinnamamides: access to alkylated 1-azaspiro[4.5]decanes

“…9,10 Our group reported the tandem oxidative C(sp 3 )-H bond activation/SO 2 elimination/C(sp 2 )-C(sp 3 ) bond formation reaction of simple cyclanes and N-phenyl-Ntosylmethacrylamides under metal-free conditions (Scheme 1(d)). 11 The spirodienone motif is widely found in natural products and organic molecules, which offers a base for the construction of organic compounds with a complex structure. 12 Especially, much effort has been spent on dearomatizing spirocyclization of phenol derivatives, which provides direct access to the highly valuable spirodienone motif and can be used in complex total syntheses.…”

An Intrinsically Conductive Phosphorus‐Doped Perovskite Oxide as a New Cathode for High‐Performance Dye‐Sensitized Solar Cells by Providing Internal Conducting Pathways

“…It was also found that DSSCs with pure MWCNTs cathode displayed a PCE of 3.71%, which was comparable with the results reported in the literature (2.69%, 2.87%, and 3.94%). [45][46][47][48] It indicates that the www.advancedsciencenews.com www.solar-rrl.com commercial MWCNTs without any special treatment should not be a high-performance electrocatalyst for IRR. The combination of perovskite and carbon material greatly enhanced the IRR activity as compared with the individual component, which can be assigned to the fact that perovskite oxide provided the active sites for IRR and the carbon material served as a highly conductive substrate as demonstrated in our previous study.…”