Metal‐Free Atom Transfer Radical Polymerization to Prepare Recylable Micro‐Adjuvants for Dendritic Cell Vaccine
Hengyuan Zhang,
Xingyu Heng,
He Yang
et al.
Abstract:In the development of dendritic cell (DC) vaccines, the maturation of DCs is a critical stage. Adjuvants play a pivotal role in the maturation of DCs, with a major concern being to ensure both efficacy and safety. This study introduces an innovative approach that combines high efficacy with safety through the synthesis of micro‐adjuvants grafted with copolymers of 2‐(methacrylamido) glucopyranose (MAG) and methacryloxyethyl trimethyl ammonium chloride (DMC). The utilization of metal‐free surface‐initiated atom… Show more
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