Metal Complexes of Amino Acids and Peptides

Farkas, Etelka; Sóvágó, Imre

doi:10.1039/9781847555250-00353

Cited by 6 publications

(2 citation statements)

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“…The Ca 2+ -binding cyclic decapeptide cyclo[Pro-Phe-Phe-Ala-Glu(OtBu)]2 is a recent addition to this family [25]. For an overview of metal-binding peptides, see [26]. The work of the Blout group not only contributed to the understanding of structural aspects of cyclopeptides, but also provided insight into their receptor properties.…”

Section: Cyclic Peptides and Pseudopeptides Containing Only α-Amino A...mentioning

confidence: 99%

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Synthetic Receptors Based on Abiotic Cyclo(pseudo)peptides

Kubik

2022

Molecules

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Work on the use of cyclic peptides or pseudopeptides as synthetic receptors started even before the field of supramolecular chemistry was firmly established. Research initially focused on the development of synthetic ionophores and involved the use of macrocycles with a repeating sequence of subunits along the ring to facilitate the correlation between structure, conformation, and binding properties. Later, nonnatural amino acids as building blocks were also considered. With growing research in this area, cyclopeptides and related macrocycles developed into an important and structurally diverse receptor family. This review provides an overview of these developments, starting from the early years. The presented systems are classified according to characteristic structural elements present along the ring. Wherever possible, structural aspects are correlated with binding properties to illustrate how natural or nonnatural amino acids affect binding properties.

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Section: Cyclic Peptides and Pseudopeptides Containing Only α-Amino A...mentioning

confidence: 99%

“…The Ca 2+ -binding cyclic decapeptide cyclo[Pro-Phe-Phe-Ala-Glu(OtBu)] 2 is a recent addition to this family [25]. For an overview of metal-binding peptides, see [26].…”

Section: Cyclic Peptides and Pseudopeptides Containing Only α-Amino A...mentioning

confidence: 99%