Metal-catalyzed synthesis of triazine derivatives

Jain, Sonika; Kumawat, Jyoti; Jain, Pankaj; Shruti, .; Malik, Prerna; Dwivedi, Jaya; Kishore, Dharma

doi:10.1007/s00706-022-02948-2

Cited by 3 publications

(2 citation statements)

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“…Many attempts have been made to substitute sulphuric acid with different catalysts. [27][28][29] The Beckmann rearrangement is performed in a highly acidic media (H 2 SO 4 ) or a combination of acetic acid, acetic anhydride, and hydrogen chloride. Because these chemicals are incompatible with a wide number of sensitive substrates.…”

Section: Various Attempts Have Been Undertaken To Perform the Beckman...mentioning

confidence: 99%

Comprehensive updates on Beckmann Rearrangement

Kaushik,

Jain,

Malik

et al. 2024

ChemistrySelect

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Beckmann rearrangement has been quite successful in the preparation of many medicinally potent scaffolds. In synthetic organic chemistry, the Beckmann rearrangement is quite popular, caprolactam is synthesized from cyclohexanone oxime on a large scale for Nylon‐6 production. The function of numerous catalysts and media in the Beckmann rearrangement has been discussed in depth in this review. In the last 20 years, Beckmann rearrangement catalysis has evolved from a potentially hazardous to a more environmentally friendly catalyst, as a result of greater usage. Catalytic performance and synthetic performance of various catalytic systems have been re‐evaluated in the present review article.

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Section: Various Attempts Have Been Undertaken To Perform the Beckman...mentioning

confidence: 99%

Comprehensive updates on Beckmann Rearrangement

Kaushik,

Jain,

Malik

et al. 2024

ChemistrySelect

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“…That approach which creates many substituted compounds directly from easily accessible starting materials using transition metalcatalyzed processes under moderate conditions has emerged as the most appealing technique of several novel synthetic methods [20,21]. Coupling processes catalyzed by transition metals and hetero-annulation [22][23][24] are excellent and practical strategies for assembling N-heterocycles [25][26][27] in organic synthesis. Due to their low toxicity, low cost, easy availability, and significant synthetic flexibility, first-row transition metals [28][29][30] have been widely used in synthetic organic chemistry.…”

Section: Introductionmentioning

confidence: 99%

Iron‐catalyzed intermolecular and intramolecular cyclization reactions of N‐heterocycles

Kaushik,

Jain,

Kishore

et al. 2024

Journal of Heterocyclic Chem

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N‐Heterocyclic compounds have been appealing pharmacophores in their use as drug production substrates. In this review paper, the cyclization of N‐heterocycles, using iron as a catalyst, and their mechanistic pathways have been highlighted and presented comprehensively. This paper will provide researchers with in‐depth knowledge of their approach to synthesis by employing a greener way rather than a conventional one. The present review firmly establishes that iron catalysts by their innate ability and inherent potential to acquire the four oxidation states coupled with their easy accessibility, inexpensive, and environment‐friendly nature have remained the mainstay in chemistry as the evergreen catalyst in the domain of organic synthesis. This review paper extensively explores iron‐catalyzed cyclization of N‐heterocycles, elucidating mechanistic pathways and emphasizing greener synthesis methods. Iron's versatility, accessibility, and eco‐friendliness solidify its position as a cornerstone in organic synthesis.

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