Metal accumulation and sublethal effects in the sea anemone, Aiptasia pallida, after waterborne exposure to metal mixtures

Brock, Jonathan; Bielmyer, Gretchen K.

doi:10.1016/j.cbpc.2013.07.001

Cited by 21 publications

(19 citation statements)

References 39 publications

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“…The mean copper accumulation after 7 and days was 33.96 and 34.44 µg.g -1 dry weight respectively. This result was comparable to accumulation patterns seen in the symbiotic anemone Aiptasia pallida, although there was a level of dose dependency in accumulation rates for A. pallida (Brock & Bielmyer 2013). Copper bioconcentration in this study was also greater than seen in another anthozoan, Anemonia viridis, with accumulation again very dependent on the exposure concentrations (Harland & Nganro 1990).…”

Section: Discussionsupporting

confidence: 80%

Predicting aqueous copper and zinc accumulation in the upside-down jellyfish Cassiopea maremetens through the use of biokinetic models

Templeman

Kingsford

2015

Environ Monit Assess

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Jellyfish have a demonstrated capability to accumulate metals within their tissues, but to date, there have been no quantitative assessments of accumulation and retention rates and patterns. Bioconcentration patterns of copper and zinc in the upside-down jellyfish Cassiopea maremetens were modelled over a 28-day study (14 days exposure followed by 14 days clearance). C. maremetens accumulated copper over 14 days with the maximum calculated copper concentrations at 33.78 μg g(-1) dry weight and bioconcentrated to 99 times water concentrations. Zinc was also accumulated during the exposure period and retained for longer. The maximum theoretical zinc concentration was 125.1 μg g(-1) dry weight with a kinetic bioconcentration factor of 104. The patterns of uptake and retention were different between the elements. The use of kinetic models provided adequate predictions of aqueous metal uptake and retention in C. maremetens. This species has the capacity to very rapidly absorb measurable metals from short-term water-metal exposure.

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Section: Discussionsupporting

confidence: 80%

Predicting aqueous copper and zinc accumulation in the upside-down jellyfish Cassiopea maremetens through the use of biokinetic models

Templeman

Kingsford

2015

Environ Monit Assess

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“…Catalase activity: An increase in the levels of CAT and RG has been reported in sea anemones exposed to copper chloride which was further intensified at low [33][34][35]. Similarly in the present study increase in CAT, RG and GST levels at decreased pH were observed which might be further intensified by environmental toxicants.…”

Section: Acetylcholine Esterase Activitysupporting

confidence: 60%

Biomarker Response of Ocean Acidification Induced Hypercapnia on Marine Bivalve Donax cuneatus, Linnaeus 1758

Anand¹

2016

JAMB

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The present study reports the investigation of the sub lethal impacts of ocean acidification induced hypercapnia (pH 7.5 and 7.0) and leakage of sub sea bed Carbon Dioxide storage sites (pH 6.5-5.5) on marine bivalve Donax cuneatus, Linnaeus 1758 collected from the Gulf of Mannar province. Fifteen days experiment was carried out in laboratory microcosms in a closely monitored environment. The impacts of Hypercapnia on Biomarker enzymes indicating neurotoxicity (Acetylcholinesterase), oxidative stress (lipid peroxidation and catalase) and phase II biotransformation of xenobiotics (glutathione S transferase, and reduced glutathione) were estimated. The increase in lipid peroxidation and catalase activities suggest hypercapnia induced oxidative stress. The decreasing pH also increased the activity of reduced glutathione and glutathione S transferase which acts as detoxifying enzymes for Hypercapnia induced toxicity however the hypercapnic conditions inhibited the levels of acetylcholine esterase which indicates the polluted environment substantiating stress induced high rate of mortality at low pH levels. The above used biomarkers thus provide a valuable tool for monitoring ocean acidification induced hypercapnic stress at a sublethal level.

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“…), and studies have demonstrated deleterious effects of heavy metals on sea anemones and corals causing tentacle retraction, endosymbiotic loss and death (Mitchelmore et al . ; Sabdono ; Brock & Bielmyer ). Understanding the molecular mechanisms involved in the stress response of cnidarians is therefore an important target of research.…”

Section: Introductionmentioning

confidence: 99%

“…Heavy metals do not decay but represent a persistent form of toxicity that is passed up the food chain and remains in the environment long after the source of the pollution is contained (Roberts et al 2010;Pan & Wang 2012). High concentrations of heavy metals found in coral skeletons were found to be related to human activities (Al-Rousan et al 2012;Chan et al 2013), and studies have demonstrated deleterious effects of heavy metals on sea anemones and corals causing tentacle retraction, endosymbiotic loss and death (Mitchelmore et al 2003;Sabdono 2009;Brock & Bielmyer 2013). Understanding the molecular mechanisms involved in the stress response of cnidarians is therefore an important target of research.…”

Section: Introductionmentioning

confidence: 99%

Early and late response of Nematostella vectensis transcriptome to heavy metals

et al. 2014

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Environmental contamination from heavy metals poses a global concern for the marine environment, as heavy metals are passed up the food chain and persist in the environment long after the pollution source is contained. Cnidarians play an important role in shaping marine ecosystems, but environmental pollution profoundly affects their vitality. Among the cnidarians, the sea anemone Nematostella vectensis is an advantageous model for addressing questions in molecular ecology and toxicology as it tolerates extreme environments and its genome has been published. Here, we employed a transcriptome-wide RNA-Seq approach to analyse N. vectensis molecular defence mechanisms against four heavy metals: Hg, Cu, Cd and Zn. Altogether, more than 4800 transcripts showed significant changes in gene expression. Hg had the greatest impact on up-regulating transcripts, followed by Cu, Zn and Cd. We identified, for the first time in Cnidaria, co-up-regulation of immediate-early transcription factors such as Egr1, AP1 and NF-κB. Time-course analysis of these genes revealed their early expression as rapidly as one hour after exposure to heavy metals, suggesting that they may complement or substitute for the roles of the metal-mediating Mtf1 transcription factor. We further characterized the regulation of a large array of stress-response gene families, including Hsp, ABC, CYP members and phytochelatin synthase, that may regulate synthesis of the metal-binding phytochelatins instead of the metallothioneins that are absent from Cnidaria genome. This study provides mechanistic insight into heavy metal toxicity in N. vectensis and sheds light on ancestral stress adaptations.

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Metal accumulation and sublethal effects in the sea anemone, Aiptasia pallida, after waterborne exposure to metal mixtures

Cited by 21 publications

References 39 publications

Predicting aqueous copper and zinc accumulation in the upside-down jellyfish Cassiopea maremetens through the use of biokinetic models

Predicting aqueous copper and zinc accumulation in the upside-down jellyfish Cassiopea maremetens through the use of biokinetic models

Biomarker Response of Ocean Acidification Induced Hypercapnia on Marine Bivalve Donax cuneatus, Linnaeus 1758

Early and late response of Nematostella vectensis transcriptome to heavy metals

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