Metabolomic profiling and accurate diagnosis of basal cell carcinoma by MALDI imaging and machine learning
Lauritz F. Brorsen,
James S. McKenzie,
Fernanda E. Pinto
et al.
Abstract:Basal cell carcinoma (BCC), the most common keratinocyte cancer, presents a substantial public health challenge due to its high prevalence. Traditional diagnostic methods, which rely on visual examination and histopathological analysis, do not include metabolomic data. This exploratory study aims to molecularly characterize BCC and diagnose tumour tissue by applying matrix‐assisted laser desorption ionization mass spectrometry imaging (MALDI‐MSI) and machine learning (ML). BCC tumour development was induced in… Show more
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