Metabolomic analysis of dietary‐restriction‐induced attenuation of sarcopenia in prematurely aging DNA repair‐deficient mice
Yupeng He,
Wei Yang,
Luojiao Huang
et al.
Abstract:BackgroundSarcopenia is characterized by loss of skeletal muscle mass and function, and is a major risk factor for disability and independence in the elderly. Effective medication is not available. Dietary restriction (DR) has been found to attenuate aging and aging‐related diseases, including sarcopenia, but the mechanism of both DR and sarcopenia are incompletely understood.MethodsIn this study, mice body weight, fore and all limb grip strength, and motor learning and coordination performance were first anal… Show more
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