Metabolites profiling and hypolipidemic/hypocholesterolemic effects of persimmon (Diosyros kaki Thumb.) by different processing procedures:in vitroandin vivostudies

Park, Soo Yeon; Oh, Eun Kyoung; Lim, Yeni; Shin, Ji-Yoon; Jung, Hee-Ah; Park, Song‐Yi; Lee, Jin-hee; Choe, Jeong‐Sook; Kwon, Oran

doi:10.4163/jnh.2018.51.4.275

Cited by 4 publications

(4 citation statements)

References 24 publications

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“…The obtained metabolite results of persimmon samples showed relatively high amounts of tannins in comparison with the investigated three samples of kiwifruits and are in line with several reports [ 5 , 6 , 11 , 12 ]. The estimation of quenching of serum proteins such as fibrinogen ( Figure 8 F, line 8) and globulin with tannic acid ( Figure 9 , line 5) are in full agreement with the amount of tannic acid in persimmon samples.…”

Section: Resultssupporting

confidence: 91%

“…The fibrinogen-to-albumin ratio index is a valuable biomarker associated with ST- elevation myocardial infarction and may be useful in the prediction of the long-term prognosis of patients with such diseases [ 26 ]. So, following the recent reports on humans discussed above and the results of the supplementation of fruits, it was shown that the triglyceride (TG)/cholesterol profile depended on the treatment of persimmon water extracts, and tannin-enriched persimmon concentrate stimulated hypocholesterolemic actions [ 6 , 53 , 54 ]. Similar action was obtained by a combination of Diospyros kaki fruit and Citrus unshiu peel mixture as a potential therapeutic agent for treating nonalcoholic fatty liver disease with the remarkable growth of obesity [ 55 ].…”

Section: Resultsmentioning

confidence: 99%

“…Persimmons ( Diospyros kaki ) are recognized as an outstanding source of biologically active components that exhibit many health benefits, such as antioxidant behavior, radical scavenging activity, antihypertensive and antiatherosclerosis activities [ 5 ]. The metabolite profiles related to triglyceride/cholesterol metabolism treated with persimmon were studied [ 6 ]. The persistent calyx of Diospyros kaki is reported to contain phenolic compounds, including condensed tannins together with phenolic components, estimated in 70% acetone extract [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

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Bioactivities of Phenolic Compounds from Kiwifruit and Persimmon

et al. 2021

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Fruit used in the common human diet in general, and kiwifruit and persimmon particularly, displays health properties in the prevention of heart disease. This study describes a combination of bioactivity, multivariate data analyses and fluorescence measurements for the differentiating of kiwifruit and persimmon, their quenching and antioxidant properties. The metabolic differences are shown, as well in the results of bioactivities and antioxidant capacities determined by ABTS, FRAP, CUPRAC and DPPH assays. To complement the bioactivity of these fruits, the quenching properties between extracted polyphenols and human serum proteins were determined by 3D-fluorescence spectroscopy studies. These properties of the extracted polyphenols in interaction with the main serum proteins in the human metabolism (human serum albumin (HSA), α-β-globulin (α-β G) and fibrinogen (Fgn)), showed that kiwifruit was more reactive than persimmon. There was a direct correlation between the quenching properties of the polyphenols of the investigated fruits with serum human proteins, their relative quantification and bioactivity. The results of metabolites and fluorescence quenching show that these fruits possess multiple properties that have a great potential to be used in industry with emphasis on the formulation of functional foods and in the pharmaceutical industry. Based on the quenching properties of human serum proteins with polyphenols and recent reports in vivo on human studies, we hypothesize that HSA, α-β G and Fgn will be predictors of coronary artery disease (CAD).

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Section: Resultssupporting

confidence: 91%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Bioactivities of Phenolic Compounds from Kiwifruit and Persimmon

et al. 2021

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“…Cholesterol is an essential raw material used by Leydig cells to drive this biological process. Several phytochemicals in ESS down‐regulate the gene expression of cholesterol biosynthesis enzymes and intestinal cholesterol transporters, while up‐regulating the gene expression of LDL receptor (Alvaro et al, 2010; Park et al, 2018; Yang et al, 2018). PUFAs stimulate the faecal excretion of cholesterol by facilitating its hepatic uptake and bile acid production (Bérard et al, 2004; Pizzini et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Role of Eruca sativa L. seeds in boosting the reproductive performance of male Japanese quails (Coturnix c. japonica)

Waly,

Abdelfattah,

Abou Khalil

et al. 2023

Animal Physiology Nutrition

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Herein we attempt to shed light on the potential improving effect of Eruca sativa seeds (ESS) on the reproductive aspects of male Japanese quails. To accomplish this objective, two groups of quails were supplemented with ESS powder at doses of 5 and 10 g/kg feed from 7 days to 140 days of age, in addition to the control group, which did not receive treatment. Forty males were reared singly in cages to evaluate sperm characters and 32 males were raised with 64 females to evaluate fertility and sperm penetrability. Sixty‐six phytochemical compounds were found according to gas chromatography–mass spectrometry analysis of ESS. The most plentiful ones are 13‐docosenoic acid methyl ester, 9‐octadecenoic acid methyl ester, and linoleic acid methyl ester. Both 5 g/kg and 10 g/kg doses of ESS showed similar effectiveness in enhancing various reproductive parameters, including gonadal index, sperm characteristics, fertility, libido, and cloacal gland attributes. However, some aspects like sperm concentration and testosterone levels exhibited a dose‐dependent response. There is no significant change in mortality rate of supplemented groups compared to the control one. ESS also caused a reduction in feed intake and an enhancement in feed conversion ratio without affecting final body weight and body weight gain. This suggests potential nutritional benefits beyond reproductive health. The low‐dose‐fed group showed a significant reduction in total cholesterol and malondialdehyde compared to the high‐dose‐fed and unfed groups. The higher dose notably increased total antioxidant capacity compared to the lower dose and control group. Despite the positive effects on male reproductive parameters, there wasn't a significant impact on hatchability percentage, indicating that while male fertility improved, it might not have directly affected the viability of the eggs. Overall, the study suggests that ESS could be a safe and promising addition to the diet of male Japanese quails to enhance their reproductive capabilities without adverse effects. The findings could have implications for poultry farming by potentially improving breeding efficiency and health outcomes in quails.

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