“…However, the mechanisms by which acetate impacts lipid metabolism are conflicting, either by inhibiting lipolysis (Ge et al, 2008; Hong et al, 2005), reducing fat accumulation through changes in fatty acid oxidation (Kondo, Kishi, Fushimi, & Kaga, 2009), reducing fatty acid synthesis (Yamashita et al, 2009), and/or reducing appetite (Frost et al, 2014). Triacetin infusion in female mongrel dogs showed that triacetin is hydrolysed intravascularly and primarily oxidized in the liver (Bleiberg et al, 1993). Additionally, triacetin‐derived acetate is rapidly taken up by the liver, hindlimb and intestine, suggesting that a small amount of acetate would be taken up by the adipose tissue (Bleiberg et al, 1993).…”