“…Pirie (1934a, b) observed the oxidation to sulphate of cysteine, cystine, glutathione, methionine and a number of other compounds by slices of rat tissues, of which liver and kidney were the most active. Medes (1939) and Medes & Floyd (1942) confirmed these findings and extended their experiments to liver breis and extracts. Sulphate was also produced by tissue slices and extracts without the addition of sulphur-containing compounds to the medium.…”