Abstract:The radioactivity administered as a single oral dose of N-[3-chloro-4-(ß-D-glucosyI [ 14C] methyl)phenyl]urea was rapidly absorbed from the gastrointestinal tract and eliminated in feces and urine by both the rat and the Japanese quail. Within 6 h after treatment 57 % and 74% of the dose was excreted by rat and quail, respectively. Of the 78% of the dose excreted by rat within 12 h, 49% was the parent glucoside, 3.6% the aglycon, and 14.6 % the aglycon acid (the carboxyphenyl derivative of the aglycon). Howev… Show more
“…3-Phenoxybenzaldehyde and its 11 metabolites were detected (189); the metabolism of the insecticidally active GABAA receptor antagonist was investigated (190); radioactive cinmethylin and its degradation products were detected (191); 14 C-8-hexachlorocyclohexane was identified after TLC separation (192); and the chromatographic behavior of chlorotoluron and its metabolites was investigated (193). 3-Phenoxybenzaldehyde and its 11 metabolites were detected (189); the metabolism of the insecticidally active GABAA receptor antagonist was investigated (190); radioactive cinmethylin and its degradation products were detected (191); 14 C-8-hexachlorocyclohexane was identified after TLC separation (192); and the chromatographic behavior of chlorotoluron and its metabolites was investigated (193).…”
Section: Autoradiography and Related Techniquesmentioning
confidence: 99%
“…TLC of degradation products of ethylenebisdithiourea on silica with acetone, acetone-water, and ethanol was reported (154). Chlorotoluron and its metabolites were chromatographed on silica gel (193). Chlorotoluron and its metabolites were chromatographed on silica gel (193).…”
Section: E Carbamates and Urea Derivativesmentioning
“…3-Phenoxybenzaldehyde and its 11 metabolites were detected (189); the metabolism of the insecticidally active GABAA receptor antagonist was investigated (190); radioactive cinmethylin and its degradation products were detected (191); 14 C-8-hexachlorocyclohexane was identified after TLC separation (192); and the chromatographic behavior of chlorotoluron and its metabolites was investigated (193). 3-Phenoxybenzaldehyde and its 11 metabolites were detected (189); the metabolism of the insecticidally active GABAA receptor antagonist was investigated (190); radioactive cinmethylin and its degradation products were detected (191); 14 C-8-hexachlorocyclohexane was identified after TLC separation (192); and the chromatographic behavior of chlorotoluron and its metabolites was investigated (193).…”
Section: Autoradiography and Related Techniquesmentioning
confidence: 99%
“…TLC of degradation products of ethylenebisdithiourea on silica with acetone, acetone-water, and ethanol was reported (154). Chlorotoluron and its metabolites were chromatographed on silica gel (193). Chlorotoluron and its metabolites were chromatographed on silica gel (193).…”
Section: E Carbamates and Urea Derivativesmentioning
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