Metabolism of furan fatty acids in fish

Sand, Donald M.; Glass, Robert L.; Olson, D.L.; Pike, Helen M.; Schlenk, Hermann

doi:10.1016/0005-2760(84)90259-5

Cited by 33 publications

(3 citation statements)

References 18 publications

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“…Gunstone et al 4) found little difference in the F acid contents between ovaries and testes of northern pike. Sand et al 23) noted testis lipids of carp to contain 40-50% F acids, whereas the roe had only 1-2 F acids in the lipids. In this study, in order to determine to F acid distribution in gonadal tissues, gonads were subdivided and their lipids analyzed.…”

Section: Resultsmentioning

confidence: 99%

Furan Fatty Acids of Lipids from Serum and Sexual Organs of Chum Salmon.

Ota¹,

Toru²

1991

NIPPON SUISAN GAKKAISHI

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Section: Resultsmentioning

confidence: 99%

Furan Fatty Acids of Lipids from Serum and Sexual Organs of Chum Salmon.

Ota¹,

Toru²

1991

NIPPON SUISAN GAKKAISHI

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“…Feeding 14 C-labeled acetate to fish revealed that the acetate is incorporated into the carboxylic side chain by chain elongation. Chain shortening of the carboxylic side chain also was observed, but acetate was incorporated neither into the furan ring nor into the alkyl side chain (95), an indication that fish synthesize neither the alkyl side chain nor the furan ring of F-acids.…”

Section: Biosynthesismentioning

confidence: 99%

Furan fatty acids: Occurrence, synthesis, and reactions. Are furan fatty acids responsible for the cardioprotective effects of a fish diet?

Spiteller

2005

Lipids

148

170

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Furan FA (F-acids) are tri- or tetrasubstituted furan derivatives characterized by either a propyl or pentyl side chain in one of the alpha-positions; the other is substituted by a straight long-chain saturated acid with a carboxylic group at its end. F-acids are generated in large amounts in algae, but they are also produced by plants and microorganisms. Fish and other marine organisms as well as mammals consume F-acids in their food and incorporate them into phospholipids and cholesterol esters. F-acids are catabolized to dibasic urofuran acids, which are excreted in the urine. The biogenetic precursor of the most abundant F-acid, F6, is linoleic acid. Methyl groups in the beta-position are derived from adenosylmethionine. Owing to the different alkyl substituents, synthesis of F-acids requires multistep reactions. F-acids react readily with peroxyl radicals to generate dioxoenes. The radical-scavenging ability of F-acids may contribute to the protective properties of fish and fish oil diets against mortality from heart disease.

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“…These acids have been elucidated in many cases to be exogenous in fish.1) They tended to be distributed in TG, in contrast to the relatively high accumulation of F acids in the SE. Such differences in the distribution of these unusual fatty acids among the lipid classes suggest that F acids possibly occur in the cresthead flounder not only by incorporation through dietary lipids, 19,20) but also by other reasons originated from fish physiology. F acids in fish show various fluctuations in their amounts and distribution in lipid classes.…”

Section: Lipid Content and Lipid Class Compositionmentioning

confidence: 99%