Metabolism of FAD, FMN and riboflavin (vitamin B2) in the human parasitic blood flukeSchistosoma mansoni
Akram A. Da’dara,
Catherine S. Nation,
Patrick J. Skelly
Abstract:Schistosomiasis is a parasitic disease caused by trematode worms of the genus Schistosoma. The intravascular worms acquire the nutrients necessary for their survival from host blood. Since all animals are auxotrophic for riboflavin (vitamin B2), schistosomes too must import it to survive. Riboflavin is an essential component of the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD); these support key functions of dozens of flavoenzymes. In this work we focus on the biochemistry of ribo… Show more
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