Metabolism and residue differences of Enrofloxacin between the brain and peripheral tissues and the resulting brain damages in crucian carp (Carassius auratus var. Pengze)
Abstract:This study aimed to explore the metabolism and residue differences of Enrofloxacin (ENR) at two doses between the brain and peripheral tissues (liver, kidney, and muscle) along with the brain damages caused by ENR in crucian carp (Carassius auratus var. Pengze). The concentrations of ENR in tissues were determined using a validated high‐performance liquid chromatography (HPLC) analysis. Relying on the hematoxylin–eosin (HE) staining method, brain damages caused by the drug were evaluated by the section of path… Show more
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