Metabolic trajectories of diabetic ketoacidosis onset described by breath analysis
Mo Awchi,
Kapil Dev Singh,
Sara Bachmann Brenner
et al.
Abstract:PurposeThis feasibility study aimed to investigate the use of exhaled breath analysis to capture and quantify relative changes of metabolites during resolution of acute diabetic ketoacidosis under insulin and rehydration therapy.MethodsBreath analysis was conducted on 30 patients of which 5 with DKA. They inflated Nalophan bags, and their metabolic content was subsequently interrogated by secondary electrospray ionization high-resolution mass spectrometry (SESI-HRMS).ResultsSESI-HRMS analysis showed that aceto… Show more
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