Metabolic syndrome in Egyptian patients with vitiligo

Sallam, Manar; Gaballah, Mohammad A.; State, Ahmed Fathy; Al-Harrass, Mohammad

doi:10.1097/01.ewx.0000513078.01555.d6

Cited by 16 publications

(77 citation statements)

References 27 publications

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“…Our discoveries were in conflict with M.Sallam et al, [12] and M.Rodríguez-Martín et al, [8] who found a lower noteworthy pervasiveness of changed WC, TGs, and low HDL-C in vitiligo patients. This might be clarify that patients with vitiligo would in general present lower CVD hazard than controls, as vitiligo patients introduced a superior lipid profile, with more elevated levels of HDL-C and lower TGs and WC values.…”

Section: Discussioncontrasting

confidence: 90%

“…S.M.Derakhshandeh-Rishehri and M.Sallam et al, [9,12] revealed a comparable outcomes to our own that we found no huge contrasts between the cases and the controls regarding age, and sex. Then, A.S.Karadag and M.Rodríguez-Martín et al, [13,8] detailed no critical contrasts could be seen in BMI and this in concurrence with our discoveries.…”

Section: Discussionsupporting

confidence: 86%

“…Then, A.S.Karadag and M.Rodríguez-Martín et al, [13,8] detailed no critical contrasts could be seen in BMI and this in concurrence with our discoveries. In any case, M.Sallam et al, [12] found that the patient gathering indicated essentially lower BMI than the benchmark group. This might be clarified by that [12] patients and controls have comparable fasting glucose and that patients with vitiligo would in general present lower CVD hazard than controls.…”

Section: Discussionmentioning

confidence: 89%

“…In any case, M.Sallam et al, [12] found that the patient gathering indicated essentially lower BMI than the benchmark group. This might be clarified by that [12] patients and controls have comparable fasting glucose and that patients with vitiligo would in general present lower CVD hazard than controls.…”

Section: Discussionmentioning

confidence: 89%

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Assessment of Serum Fatty Acid Binding Protein 4 in Patients with Vitilgo

Ibrahim

Mustafa

El-Shimi

et al. 2020

Benha Journal of Applied Sciences

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Although FABP4 is the most commonly known isoform of FABP, no studies have investigated its role in vitiligo. Therefore, our aim was to assess serum FABP4 level in patients with vitiligo.This is a prospective case-control study and was include50 patients suffering from vitilgo. In addition, 30 apparently healthy individuals. Estimation of serum level of FABP4 using Enzyme Linked Immunosorbent assay (ELISA). Serum FABP4 was significantly higher in vitiligo patients when compared to control group (p<0.001).Higher FABP4 level was significantly associated with overweight. FABP4 showed significant positive correlation with BMI, TC, TG, LDL VASI score, significant negative correlations with HDL in cases. FABP4 could be used to predict metabolic syndrome and cardiovascular disease development in vitiligo patients.. In addition, lipid profile, BMI and VASI of the vitiligo are significantly correlated with FABP4.

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Section: Discussioncontrasting

confidence: 90%

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 89%

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Assessment of Serum Fatty Acid Binding Protein 4 in Patients with Vitilgo

Ibrahim

Mustafa

El-Shimi

et al. 2020

Benha Journal of Applied Sciences

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“…Despite numerous studies, contradictory results have been reported regarding the association between vitiligo and atherosclerotic cardiovascular disease (CVD) risk; some studies revealed lower cardiovascular risk in vitiligo patients than controls (Rodríguez‐Martín et al., 2013; Sallam et al., 2017).…”

Section: Introductionmentioning

confidence: 99%

Support for increased cardiovascular risk in non‐segmental vitiligo among Egyptians: A hospital‐based, case–control study

Azzazi

Mostafa

Sayed

et al. 2020

Pigment Cell Melanoma Res

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Background Data have been accumulating in the past few years that identify vitiligo as a disorder with systemic implications. Results and methods In this hospital‐based, cross‐sectional, case–control study, 50 patients with non‐segmental vitiligo and 50 age‐ and sex‐matched controls underwent analysis of serum lipid profile, oxidative stress biomarkers and carotid duplex. Hydrogen peroxide (H2O2) and malondialdehyde (MDA) were significantly higher in patients than controls (p‐value < .001, <.001, respectively); on the other hand, total antioxidant capacity (TAC) was significantly lower in patients than controls (p‐value = .001). A significantly higher percentage of patients had hypercholesterolemia and borderline high, high or very high levels of LDL‐C, compared to controls (p‐value = .001 and .001, respectively). Atherosclerotic plaques and increased common carotid intima media thickness were significantly detected in patients versus controls. Discussion Results of the present study suggest that a subset of patients with vitiligo are at a higher risk of developing dyslipidemia and atherosclerosis, which might increase their future risk for the development of cardiovascular disease. Confirmation of these findings would subsequently influence investigative and the treatment strategies in the management plan of vitiligo patients in the near future. Significance Vitiligo patients might be at a higher risk of developing dyslipidemia and atherosclerosis, which might increase their risk for the development of cardiovascular disease necessitating prophylactic measures to improve prognosis. Our results might influence the investigative and treatment strategies in the management plan of vitiligo patients in the near future.

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Comorbidities in Patients with Vitiligo: A Systematic Review and Meta-Analysis

Lee

Seo

et al. 2023

Journal of Investigative Dermatology

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Metabolic syndrome in Egyptian patients with vitiligo

Cited by 16 publications

References 27 publications

Assessment of Serum Fatty Acid Binding Protein 4 in Patients with Vitilgo

Assessment of Serum Fatty Acid Binding Protein 4 in Patients with Vitilgo

Support for increased cardiovascular risk in non‐segmental vitiligo among Egyptians: A hospital‐based, case–control study

Comorbidities in Patients with Vitiligo: A Systematic Review and Meta-Analysis

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