Metabolic syndrome as a predictor of cardiovascular diseases and type 2 diabetes

Abstract

Background: The incidence of cardiovascular disease (CVD), coronary heart disease (CHD), and type 2 diabetes mellitus (T2DM) in people with the metabolic syndrome has not been thoroughly established (at least 3 of the following: abdominal adiposity, low HDL cholesterol, high triglycerides, hypertension, and impaired fasting glucose). The goal was to look at the relationship between metabolic syndrome traits and the risk of CVD, CHD, and T2DM. Methods and Results: Over the course of two years, the researchers followed a group of 300 middle-aged persons for the development of new CVD, CHD, and T2DM. Out of 300 subjects, who did not have CVD or T2DM at either visit, the prevalence of the metabolic syndrome (≥3 of 5 traits) was 25.67% (n=77). During follow-up, there were 8 cases of total CHD, 13 cases of CVD and 18 cases of T2DM. Waist girth, BMI, systolic and diastolic BP was significantly (p<0.05) higher in subjects with metabolic syndrome as compared to subjects without metabolic syndrome. Abnormal cholesterol profile was found more in subjects with metabolic syndrome as compared to subjects without metabolic syndrome.