Metabolic Syndrome and Risk of Amyotrophic Lateral Sclerosis: Insights from a Large‐Scale Prospective Study
Junwei Zhang,
Wen Cao,
Jiali Xie
et al.
Abstract:ObjectiveAlthough metabolic abnormalities are implicated in the etiology of neurodegenerative diseases, their role in the development of amyotrophic lateral sclerosis (ALS) remains a subject of controversy. We aimed to identify the association between metabolic syndrome (MetS) and the risk of ALS.MethodsThis study included 395,987 participants from the UK Biobank to investigate the relationship between MetS and ALS. Cox regression model was used to estimate hazard ratios (HR). Stratified analyses were performe… Show more
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