Metabolic syndrome and Framingham risk score for prediction of cardiovascular events in Caribbean Indian patients with blood glucose abnormalities

Jaquet, Antoine; Deloumeaux, Jacqueline; Dumoulin, Maryse; Bangou, J.; Donnet, J.-P.; Foucan, Lydia

doi:10.1016/j.diabet.2007.10.005

Cited by 11 publications

(13 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the IDF criteria, a study found no relationship with PAD in a population of patients aged 50 to 75 years, without specification of diabetes status [22]. The same results were found in a population of Indian patients [24]. A study showed a better association for IDF criteria than for the AHA / NHLBI criteria, in contrast to our study [26].…”

Section: Discussionsupporting

confidence: 53%

“…Several studies found an association of PAD with MS according to the WHO criteria [19,20] unlike the study by Wong et al [21]. Concerning the association of PAD with MS according to NCEP-ATPIII, several studies found an association and others did not [19,22-24]. The study by Larsson et al goes in the direction of ours, especially since it is cohort study [19].…”

Section: Discussionmentioning

confidence: 63%

See 1 more Smart Citation

Metabolic syndrome for sub-Saharan Africans diabetes with peripheral arterial disease: a case-control study

et al. 2014

View full text Add to dashboard Cite

BackgroundCurrently, there is no value for the definition of abdominal obesity by measuring waist circumference in the Sub-Saharan Africa. Several definitions of metabolic syndrome (MS) have disparities concerning use of waist circumference, including International Diabetes Federation (IDF), American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) and National Cholesterol Education Program-Adult Treatment Panel III (NCEP-ATPIII) definitions. The aim of the study was to determine what value of waist circumference should be used and whether to use it as obligatory criterion in the metabolic syndrome in case of peripheral arterial disease (PAD).MethodsWe conducted a case–control study in Cameroon. We included patients with diabetic foot and type 2 diabetes and excluded those with an Ankle Brachial Index (ABI) >?1.3. Cases were defined as patients with ABI?≤?0.9 and controls with ABI >?0.9. The significant p value was < 0.05 and odds ratio (OR) with 95% confidence interval was used to measured risk for have PAD with MS.ResultsWe included 19 cases and 48 controls. The risk for having PAD with MS are for the IDF: OR = 4.7 (1.4-15.1), p = 0.008, for the AHA / NHLBI: OR = 5.8 (1.5-22.5), p = 0.007, for the NCEP-ATPIII: OR = 1.8 (0.6-5.6), p = 0.286.ConclusionAbdominal obesity should be defined according to the recommendations of the IDF and AHA / NHLBI and should not be an obligatory criterion in the definition of MS for research risk to have PAD on sub-Saharan Africa.

show abstract

Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 63%

Metabolic syndrome for sub-Saharan Africans diabetes with peripheral arterial disease: a case-control study

et al. 2014

View full text Add to dashboard Cite

show abstract

“…MetS is a stronger predictor of diabetes while FRS appears better at predicting coronary heart disease [10]. Furthermore, MetS failed to identify subgroups at high cardiovascular risk in the short term (8.5 years), unlike the FRS, in Caribbean Indians with blood glucose abnormalities [31]. …”

Section: Discussionmentioning

confidence: 99%

Lifestyle and Dietary Factors Associated with the Evolution of Cardiometabolic Risk over Four Years in West-African Adults: The Benin Study

et al. 2013

View full text Add to dashboard Cite

Aim. To assess in adults from Benin changes in cardiometabolic risk (CMR) using both the Framingham risk score (FRS) and metabolic syndrome (MetS) and to examine the effects of diet, and lifestyles, controlling for location and socioeconomic status. Methods. Apparently healthy subjects (n = 541) aged 25–60 years and randomly selected in the largest city, a small town, and rural areas were included in the four-year longitudinal study. Along with CMR factors, socioeconomic, diet and lifestyle data were collected in individual interviews. A food score based on consumption frequency of four “sentinel” food groups (meat and poultry, dairy, eggs, and vegetables) was developed. Lifestyle included physical activity, alcohol and tobacco use. Education and income (proxy) were the socioeconomic variables. Results. Among the subjects with four-year follow-up data (n = 416), 13.5% were at risk at baseline, showing MetS or FRS ≥ 10%. The incidence of MetS and FRS ≥ 10% during follow-up was 8.2% and 5%, respectively. CMR deteriorated in 21% of subjects. Diet and lifestyle mediated location and income effects on CMR evolution. Low food scores and inactivity increased the likelihood of CMR deterioration. Conclusion. Combining MetS and FRS might be appropriate for surveillance purposes in order to better capture CMR and inform preventive measures.

show abstract

“…Areas under the receiver-operating characteristic (ROC) curves for FRS vs. the number of metabolic factors were 0.68 vs. 0.59 for CHD, 0.60 vs. 0.70 for type 2 DM and 0.66 vs. 0.55 for stroke (p<0.001 for all) 41). From another study showing whether MetS may improve identification of individuals at risk of CHD, comparison of ROC indicated that the MetS did not improve the CHD risk prediction beyond the level achieved by the FRS 39). Therefore, MetS may be used as the first line approach to treat the risk of ASCVD or diabetes.…”

Section: Framingham Risk Score Versus Metabolic Syndromementioning

confidence: 93%

Linkage of Epidemiologic Evidence With the Clinical Aspects of Metabolic Syndrome

Jee

2012

Korean Circ J

View full text Add to dashboard Cite

Metabolic syndrome (MetS) is characterized by a cluster of cardiovascular risk factors, such as hypertension, glucose intolerance, high triglycerides, and a low high density lipoprotein-cholesterol level. MetS is known to be associated with cardiovascular diseases. In order to diagnose MetS, definitions such as National Cholesterol Education Program Adult Treatment Panel III, American Heart Association/National Heart Lung and Blood Institute, International Diabetes Federation, World Health Organization, European Group for the Study of Insulin Resistance and American College of Endocrinology are widely used. However, using different criteria may lead to confusion regarding the diagnosis and treatment of patients with MetS in the primary care setting. Our objected was to review 3 aspects concerning MetS using the Metabolic Syndrome Research Initiatives study of 123892 healthy Koreans (1994-2001) that had a maximum follow-up of 12 years. The 3 aspects were reviewed by determination of the association of MetS with the development of atherosclerotic cardiovascular disease (ASCVD) and ischemic heart disease (IHD). Based on our findings, each metabolic factor associated with MetS was not weighted equally. The hazard ratio (HR) was higher in individuals with higher glucose compared with the HR in individuals with higher body mass index. Individuals with pre-MetS (having 1 or 2 metabolic factors) had 1.5-2.3 fold higher risk of developing ASCVD and IHD in both genders. In the presence of MetS, both singly and in combination, precede the development of ASCVD and IHD and individuals with pre-MetS must not be ignored as there is no apparent threshold in defining MetS. Furthermore, MetS may complement the Framingham Risk Score and can be used as the first line approach to treat the ASCVD or IHD.

show abstract

Metabolic syndrome and Framingham risk score for prediction of cardiovascular events in Caribbean Indian patients with blood glucose abnormalities

Cited by 11 publications

References 12 publications

Metabolic syndrome for sub-Saharan Africans diabetes with peripheral arterial disease: a case-control study

Metabolic syndrome for sub-Saharan Africans diabetes with peripheral arterial disease: a case-control study

Lifestyle and Dietary Factors Associated with the Evolution of Cardiometabolic Risk over Four Years in West-African Adults: The Benin Study

Linkage of Epidemiologic Evidence With the Clinical Aspects of Metabolic Syndrome

Contact Info

Product

Resources

About