Metabolic syndrome and common urological conditions: looking beyond the obvious

Rees, Jonathan; Kirby, Mike

doi:10.1002/tre.393

Cited by 5 publications

(6 citation statements)

References 37 publications

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“…Metabolic syndrome, a cluster of risk factors for cardiovascular disease, is also a major public health concern. It is extremely common, affecting ~25% of the global adult population, and is increasing at a substantial rate . Compared with subjects without metabolic syndrome, those with it are twice as likely to die from a heart attack or stroke, and have a five times greater risk of developing type 2 diabetes .…”

Section: Introductionmentioning

confidence: 99%

Prevalence of metabolic syndrome and its components among men with and without clinical benign prostatic hyperplasia: a large, cross‐sectional, UK epidemiological study

DiBello

Ioannou²,

Rees³

et al. 2015

BJU International

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ObjectivesTo compare the prevalence of metabolic syndrome and the components of metabolic syndrome in men aged ≥50 years with and without clinical benign prostatic hyperplasia (BPH). Subjects and MethodsThis was a cross-sectional study using the UK Clinical Practice Research Datalink (CPRD). Men were selected from the CPRD who were aged ≥50 years and still registered as of 31 December 2011. Cohort 1 included men with clinical BPH, and cohort 2 men without clinical BPH who were matched 1:1 to those in cohort 1 by general practice, year of birth and previous years of available history (1-<2, 2-<3, 3-<4, ≥4 years of available history). The prevalence of metabolic syndrome and its components (for men alive and still registered in the CRPD as of 31 December 2011) was calculated using all available history (lifetime prevalence) and medical history from 2010 and 2011 (current prevalence). Crude odds ratios and 95% confidence intervals for the occurrence of metabolic syndrome and the occurrence of the components of metabolic syndrome were calculated by comparing men with and without BPH. ResultsA total of 26.5% of men with clinical BPH had metabolic syndrome compared with 20.9% of matched controls without clinical BPH (absolute difference 5.6%; P < 0.001); men with clinical BPH were therefore significantly more likely to have metabolic syndrome than matched controls without clinical BPH. Significantly greater proportions of men with clinical BPH also had each component of metabolic syndrome compared with matched controls without clinical BPH. The presence of clinical BPH was associated with a 37% increased odds of having metabolic syndrome (for both lifetime prevalence and current prevalence) compared with matched controls without clinical BPH. ConclusionsThere is a significant cross-sectional association between clinical BPH and metabolic syndrome in the UK primary care population.

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Section: Introductionmentioning

confidence: 99%

Prevalence of metabolic syndrome and its components among men with and without clinical benign prostatic hyperplasia: a large, cross‐sectional, UK epidemiological study

DiBello

Ioannou²,

Rees³

et al. 2015

BJU International

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“…The association between the metabolic syndrome and erectile dysfunction has been described already in this journal. 6 This is clearly another urological issue that should provoke consideration of OSA as an underlying factor.…”

Section: Erectile Dysfunctionmentioning

confidence: 99%

Nocturia and obstructive sleep apnoea

Dawson

2015

Trends Urol & Men's Health

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“…It is well established that erectile dysfunction has strong associations with type 2 diabetes mellitus, cardiovascular disease, obesity and sedentary lifestyle. Less well known links are also seen with prostate cancer, renal calculi, hypogonadism and overactive bladder [5]. We are familiar with carrying out cardiovascular risk assessment, screening for diabetes and giving lifestyle advice to men with erectile dysfunction.…”

Section: The Prostate: a Gateway To Men's Healthmentioning

confidence: 99%