Metabolic Syndrome and Chronic Laryngitis

Abstract

Metabolic syndrome (MetS) is associated with a higher risk of morbidity and/or mortality for various chronic diseases. The aim of this study was to investigate the relationship of chronic laryngitis (CL) with MetS and its components in a representative Korean population.Data from the Korean National Health and Nutrition Examination Survey (2008–2010) were analyzed. A total of 10,360 adults who had undergone otolaryngological examination were evaluated.The prevalence of CL in the study population was 3.1%. The prevalence of MetS was significantly higher in patients with CL than in those without CL for both sexes (men: 34.7 ± 4.0% versus 25.9 ± 0.8%, P = 0.0235; women: 40.6 ± 5.3% versus 23.7 ± 0.7%, P = 0.0003). Elevated fasting glucose, triglycerides, and blood pressure, however, were only significantly associated with CL in women. After controlling for confounders, CL was only significantly associated with MetS in women (odds ratio: 2.159; 95% confidence interval: 1.2974, 3.594). Furthermore, the association between CL and MetS was most robust in women who were classified as obese.In Korea, MetS and its components are significantly associated with CL in women.

Korean survey data reveals an association of chronic laryngitis with tinnitus in men

“…However, only BMI and DM were associated with CL in women. Our results for several of these parameters differ from those of previous studies [ 14 , 21 ].…”

“…The increase in social activity related to the increase of the education level is likely to have decreased the incidence of these diseases or the self-questionnaire response rate [ 5 , 6 ]. The atherosclerosis process accelerated by MetS causes deterioration of tinnitus, while CL, which is caused by laryngopharyngeal reflux in patients with central obesity, which represents MetS, is a common cause of voice change [ 14 , 21 ]. Depressed mood is one of the psychosocial causes of laryngitis and tinnitus, but the predominantly male tendency in men has not previously been reported [ 22 , 23 ].…”

Epidemiological association of olfactory dysfunction with hearing loss and dysphonia in the Korean population

“…[ 18 , 19 ] However, research on the relationship between voice dysfunction and MetS is scarce. We have reported a significant association between MetS and chronic laryngitis in Korean women, [ 20 ] and gastroesophageal reflux disease is known to be common in patients with obesity and chronic laryngitis. Patients with MetS would be expected to develop chronic laryngitis and gastroesophageal reflux disease in association with dysphonia.…”

Features of the Mukoso-Associated Tissue of the Larynx in Chronic Egeneum-Polypous Laringitis

“…Корейские исследователи отмечают, что хронический ларингит обычно развивается постепенно и основные признаки и симптомы могут усиливаться и ослабевать в течение длительных периодов времени, при этом хронический ларингит редко считается инфекционным процессом [14]. Некоторые исследователи отмечают частое сочетание хронического ларингита с наличием метаболического синдрома, с преобладанием женской популяции в ассоциации метаболического синдрома и хронического ларингита, однако, причина гендерной разницы до конца не ясна [14]. В последние десятилетия большое значение в генезе многих заболеваний придается техногенному загрязнению окружающей среды.…”

“…В последние десятилетия большое значение в генезе многих заболеваний придается техногенному загрязнению окружающей среды. В силу анатомо-физиологических особенностей гортань подвергается действию большого количества ингаляционных агрессивных ирритантов, включая аллоантигены, токсичных компонентов табачного дыма, кислого содержимого желудка при ГЭРБ и природных поллютантов [14][15][16][17]. Иммунная система верхних дыхательных путей активно участвует в реакциях иммунного реагирования или толерантности по отношению собственных или аллоантигенов [16,[18][19][20][21]…”