Metabolic Syndrome; Agreement Between Metabolic Syndrome Diagnostic Criteria Among Type 2 Diabetes Mellitus Patients

Abstract

ABSTRACT… Background: Metabolic syndrome and diabetes mellitus are the modifiable risk factors of cardiovascular diseases that double the chance of illness when occur together. Little work has been reported on the superlative criteria to diagnose metabolic syndrome among diabetics from the country. Therefore, the study was aimed to find the agreement between metabolic syndrome diagnostic criteria among type 2 diabetics. Methods: The retrospective data of 373 known type 2 diabetics who had reported history of taking antidiabetic medicines was analyzed. The new International Diabetes Federation definition, the World Health Organization criteria and the NCEP Adult Treatment Panel III criteria were used to diagnose metabolic syndrome. Data was analyzed by using Statistical Package for Social Sciences version 21. Results: Mean age of 373 diabetics was 49±10 years. Participants included 36.5% males and 63.5% females. Mean BMI, WC and BP were high in females; while HDL-C was low in males (p <0.05). The frequency of MS by ATP III, IDF and WHO criteria were 88.2%; 87.4%; and 86.3%, respectively. Significant association was present between femininity, higher socioeconomic status and MS (p <0.05). ATP III criteria diagnosed the maximum number of MS followed by IDF and WHO criteria. The highest agreement was found between ATP III and IDF criteria (k 0.487). More than 85.0% diabetics were diagnosed as true positive and true negative on all three criteria. The disagreement between the studied criteria ranged from 5.1% to 8.0%. Conclusion:The ATP III, IDF and WHO criteria can equally be used to diagnose metabolic syndrome among type 2 diabetics in the settings. However, ATP III and IDF criteria have an edge over WHO criteria. Increased rate of metabolic syndrome among diabetics have need of serious attention to reduce the risk of cardiovascular events. Key words:Diabetes Mellitus Type 2, Metabolic Syndrome X, Obesity, Body Mass Index, Waist Circumference, Blood Pressure, Hypertriglyceridemia, Prevalence.

Metabolic syndrome among adults with type 2 diabetes in a Saudi teaching hospital: A comparative prevalence study using WHO and ATP III definitions

“…The agreement of these criteria as shown by the κ statistics was 0.751 (p < 0.001). Previous studies also reported a good agreement between the WHO and ATP criteria,7,17,18 with a κ statistic of 0.56 in one report 17. In another hospital-based study that included 373 known cases of T2DM,18 investigators found good agreement between the WHO and ATP III criteria ( κ = 0.366; P < 0.001).…”

Risk factors of previously undiagnosed and known untreated hypertension among patients with Type-2 diabetes mellitus

“…In the present study, overall rate of HTN 58.1% exhibit that HTN was a common comorbid condition of T2DM in the settings. Although, it was equivalent to 59.5% HTN observed in Ethiopian diabetics 9 , but was markedly lower than of 70.5% 10 and 74.0% 11 in Pakistani diabetics, 72.4% in Jordanian diabetics 8 , 79.4% in Spanish diabetics 12 , and 83.4% in Emirati diabetics. 13 The previously undiagnosed HTN 25.3% suggesting that every 4 th diabetic remain with undiagnosed HTN in the settings was lower than 37.4% undiagnosed HTN in Spanish diabetics 12 , but three times higher than 7.0% in Jordanian diabetics.…”

Síndrome metabólica em pessoas vivendo com HIV: prevalência e concordância de critérios

“…(17)(18)(19) A concordância substancial entre os critérios da IDF e do NCEP-ATPIII dos nossos achados apoia o que tem sido evidenciado na literatura em estudos com PVHIV e outros grupos. (9,(19)(20)(21) O resultado dessa concordância implica que esses critérios podem classificar o mes-mo indivíduo com SM, o que pode ser justificado pela utilização de quatro componentes metabólicos com o mesmo parâmetro de referência. A divergência dos critérios está na CA, que possui ponto de corte diferente, no critério da IDF é menor, comparado ao do NCEP-ATPIII.…”