Metabolic signature might be an option to identify patients with early CP

In silico method to maximise the biological potential of understudied metabolomic biomarkers: a study in pre-eclampsia

“…We read with interest the study by Adam et al reporting a textbook-level pipeline for biomarker identification in metabolomic datasets 1 2. This study pointed to a long-standing issue in metabolomic studies.…”

Alcohol consumption and smoking dose-dependently and synergistically worsen local pancreas damage

“…Our previous international cohort analysis showed that the proportion of patients developing CP is exponentially and directly associated with the number of acute pancreatitis (AP) episodes, thus strengthening the focus on the challenging task of diagnosing CP early 3 4. However, in addition to diagnosing early, we should also focus on preventive interventions, before the damage becomes irreversible.…”

Clinical Characteristics of Patients With Chronic Pancreatitis With or Without Prior Acute Pancreatitis Are Different

“…The second attack not only is limited to AP but also may also be related to stress, ischemia, alcohol, etc. The SAPE hypothesis has attracted the attention of many scholars and was considered to be extremely important for CP development, 4,5 which is reflected in the studies about the subsequent natural course of CP. Nearly all cohorts of natural course CP focused on the follow-up of patients after the first AP onset 6–9 .…”